Plain-spoken notes on the compounds we supply — what the literature shows, how to read a COA, and the protocols that protect your data. Cited, never hyped.
In the news
At the FDA's July 2026 compounding panel, six peptides passed and one failed: emideltide (DSIP). Why that single rejection is the most revealing vote…
Methods & QC
PeptiVerse, published in Nature Communications in July 2026, predicts peptide developability from sequence or SMILES. What it does, and what it cannot.
In the news
Samsung Biologics has bid CHF 1.46bn for Swiss peptide CDMO PolyPeptide. A sober look at what the deal says about manufacturing capacity, and what…
Metabolic & longevity
Survodutide's phase 3 body-composition substudy reported 34% less visceral fat and 63% less liver fat. What the lean-mass number does and doesn't show.
Metabolic & longevity
Petrelintide and amycretin put amylin receptor agonism to the test: less weight loss than incretins, far better GI tolerability. RUO reference overview.
In the news
Lilly's retatrutide passed TRIUMPH-2 and TRIUMPH-3 in July 2026 — but missed on cardiovascular events, and the FDA filing slipped to Q1 2027. An…
In the news
An FDA panel recommended six of seven peptides for the 503A compounding list on 23-24 July 2026. That is not approval. What the vote…
In the news
Which peptides Andrew Huberman has said he personally uses — pinealon, BPC-157, sermorelin — and what the primary literature actually shows about each.
In the news
Bryan Johnson has trialed CJC-1295, HGH, tirzepatide, cerebrolysin, epithalon, follistatin and BPC-157. A sourced look at what he measured, kept, and dropped.
Metabolic & longevity
A 2026 Copenhagen study reports MOTS-c improved intrinsic muscle mitochondrial quality in mice via PGC-1α and AMPK — without more mitochondria. RUO analysis.
Metabolic & longevity
Mitochondrial-derived peptides (MDPs) like humanin and MOTS-c are encoded inside mtDNA and act like hormones. What the cell, animal and human data actually show.
Metabolic & longevity
Exendin-4, the founding molecule of the GLP-1 drug class, was isolated from Gila monster venom by John Eng in 1992. The science-history behind the…
Occasional, considered notes on the compounds and the literature. No noise.
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