Plain-spoken notes on the compounds we supply — what the literature shows, how to read a COA, and the protocols that protect your data. Cited, never hyped.
Methods & QC
How Limulus amebocyte lysate (LAL) from horseshoe crab blood became the endotoxin test behind every injectable's COA — plus the recombinant Factor C alternative.
Metabolic & longevity
A deflationary scorecard of popular longevity compounds ranked by real human RCT evidence: rapamycin, metformin, NAD precursors, spermidine, urolithin A and more.
Hormonal
A ranking of GH secretagogues — tesamorelin, MK-677, GHRP-2, sermorelin, CJC-1295, ipamorelin — by the quantity and quality of human and regulatory evidence, not…
Metabolic & longevity
An evidence-anchored ranking of senolytics — Dasatinib+Quercetin, fisetin, navitoclax, FOXO4-DRI — showing what human and mouse data actually support, and where the field has…
In the news
Joe Rogan says he uses BPC-157 and TB-500 to heal injuries. We fact-check the claims against the actual literature — what holds up, what…
In the news
A source-checked look at where Peter Attia actually stands on NMN, rapamycin, metformin, GLP-1 drugs and BPC-157 — and where popular hype runs past…
In the news
A source-checked look at Gary Brecka's claims on methylene blue, BPC-157, NAD+ and hydrogen — what the literature actually shows, and where certainty outruns…
Hormonal
DES(1-3)IGF-1 is a natural truncated IGF-1 missing three N-terminal residues, giving reduced IGFBP binding, higher in-vitro potency and a short half-life.
Metabolic & longevity
BAM15 is a mitochondrial uncoupler studied in cell and rodent metabolic research. What it is, how it works, the evidence, and why it is…
Metabolic & longevity
Cagrilintide (AM833) is a long-acting amylin analogue and dual amylin/calcitonin receptor agonist. Its chemistry, receptor pharmacology, and trial evidence, RUO.
Hormonal
Follistatin-344 (FS344) is the follistatin cDNA isoform used in AAV gene-therapy muscle trials. What it binds, how it differs from FS288, and what the…
Nootropics
Bromantane (Ladasten) is a Russian actoprotector that raises dopamine synthesis enzymes rather than blocking reuptake. What the rodent and clinical literature actually shows.
Occasional, considered notes on the compounds and the literature. No noise.
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