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Gut

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“Leaky Gut” Examined: Zonulin, Tight Junctions and Larazotide

A myth-versus-mechanism fact-check on one of wellness's most abused phrases. The intestinal barrier is real biology; “leaky gut” as a catch-all diagnosis is not — and the one peptide that…

Jun 2026 · 7 min read

Gut

What Is Larazotide? The One “Leaky Gut” Peptide That Reached a Phase III Trial

Larazotide (AT-1001) is an eight-amino-acid peptide designed to tighten the gut's molecular seams by antagonising the zonulin pathway. It is the only “leaky gut”…

Jun 2026 · 9 min read

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