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Plain-spoken notes on the compounds we supply — what the literature shows, how to read a COA, and the protocols that protect your data. Cited, never hyped.

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HBT1: Takeda’s AMPA Receptor Potentiator, One Paper and Everything Else That Is Known Nootropics
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HBT1: Takeda’s AMPA Receptor Potentiator, One Paper and Everything Else That Is Known

HBT1 is a Takeda AMPA receptor potentiator known from one 2018 in vitro paper: identity, binding, the 5YBF structure, zero human trials, and what is missing.

Oct 2026 · 24 min read
EloraTZP vs Retatrutide: What the Three Datasets Show In the news

EloraTZP vs Retatrutide: What the Three Datasets Show

A Lilly slide shows 29% weight loss in 31 weeks with eloralintide plus tirzepatide. Only 3 of 12 had data, and it can't be…

Oct 2026 · 6 min read
In the news

Novo’s $1.4 Billion Bet on Oral Macrocycles: What a Deal Validates and What It Doesn’t

Novo signed with Orbis for up to $1.4bn on oral macrocycles. Against two 2026 approvals, what the deal establishes and what it does not.

Sep 2026 · 7 min read
In the news

Chemically Pure, Biologically Contaminated: What Endotoxin Testing Measures

Three 2026 recalls traced to one contaminated raw material show why chemical purity and biological contamination are different questions.

Sep 2026 · 7 min read
In the news

It Was Sold as Retatrutide. The Regulator’s Lab Found No Retatrutide at All

The TGA tested a vial sold as retatrutide after a hospitalisation: no retatrutide, and about eight times the semaglutide of registered products.

Sep 2026 · 8 min read
Methods & QC

Analysing Modafinil Analogues: Why GC Misleads

Modafinil, adrafinil, CRL-40,940 and CRL-40,941 degrade in the GC injector. What the literature says about method selection for this family.

Sep 2026 · 5 min read
In the news

Flmodafinil and Fladrafinil on the 2026 WADA Prohibited List

WADA named flmodafinil and fladrafinil under class S6 in 2026. Why it adds examples rather than a new ban, and what it means for…

Sep 2026 · 8 min read
ERR Agonist Evidence Atlas Metabolic & longevity

ERR Agonist Evidence Atlas

Explore 5 selected primary studies on the chemically distinct ERR agonists SLU-PP-332 and SLU-PP-915. Each record identifies the experimental model, reported finding and limits…

Sep 2026 · 5 min read
What the FDA Is About to Debate on Peptide Impurities, Sameness and Manufacturing Regulation

What the FDA Is About to Debate on Peptide Impurities, Sameness and Manufacturing

The FDA and CRCG hold a two-day workshop on the generic GLP-1 pathway on 23 and 24 September 2026. The agenda names every point…

Sep 2026 · 7 min read
The Global Peptide Manufacturing Arms Race Has Begun In the news

The Global Peptide Manufacturing Arms Race Has Begun

Samsung Biologics opened a CHF 1.46 billion tender for PolyPeptide on 15 September, with 55.65% of shares already committed. CordenPharma closed its AmbioPharm acquisition…

Sep 2026 · 7 min read
The Oral Peptide Revolution: How Drug Designers Are Breaking the Bioavailability Barrier Methods & QC

The Oral Peptide Revolution: How Drug Designers Are Breaking the Bioavailability Barrier

Icotrokinra, approved in March 2026, is a 13-amino-acid cyclic peptide taken as a daily tablet that beat both placebo and an oral small molecule…

Sep 2026 · 7 min read
From Grey Market to $80 Billion TAM? Why Wall Street Is Suddenly Paying Attention to Peptides In the news

From Grey Market to $80 Billion TAM? Why Wall Street Is Suddenly Paying Attention to Peptides

An FT Lex column put potential US peptide sales near $80bn a year. Analysts quoted by Reuters put the market regulatory change would unlock…

Sep 2026 · 8 min read
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