Plain-spoken notes on the compounds we supply — what the literature shows, how to read a COA, and the protocols that protect your data. Cited, never hyped.
Metabolic & longevity
Tirzepatide beat semaglutide head-to-head on weight loss in a randomised trial. Here is what the human data actually establish — and the hard line…
Metabolic & longevity
The same growth signalling that builds muscle is the one whose quieting extends lifespan in animals. An honest look at a paradox biology has…
Metabolic & longevity
MOTS-c is a 16-amino-acid peptide encoded inside the mitochondrial genome itself, studied as an exercise-responsive metabolic signal. The biology is genuinely striking — but…
Metabolic & longevity
NAD+ falls with age and an entire industry promises to refill it. But “raises NAD+” and “slows ageing” are two different claims — and…
Metabolic & longevity
The dream of a molecule that delivers a workout’s metabolic rewards without the workout is one of longevity’s most seductive ideas. Examined honestly, it…
Metabolic & longevity
A synthetic pan-agonist of the estrogen-related receptors, studied as an “exercise mimetic” that switches on the oxidative-metabolism programme a workout normally triggers. Here is…
Metabolic & longevity
NAD+ is the redox coenzyme every cell uses to make energy and to fuel its sirtuins and PARPs — and its levels fall with…
Metabolic & longevity
AOD-9604 is a synthetic fragment of human growth hormone, engineered to keep a fat-metabolising signal while shedding the growth. It became a famous “fat-burning…
Metabolic & longevity
Tesofensine (NS2330) is a small-molecule triple monoamine reuptake inhibitor that produced some of the largest weight-loss figures of the pre-GLP-1 era in human obesity…
Metabolic & longevity
NMN evidence card: 25 human studies checked one by one for between-group results, funding and registration; 11 trials with no article; EU, US and…
Metabolic & longevity
How metabolic research moved from a single receptor to two to three — and what each added hormone receptor changed in the preclinical and…
Metabolic & longevity
Two synthetic peptides that are almost always studied as a pair: one mimics ghrelin, the other mimics GHRH. A research primer on how each…
Occasional, considered notes on the compounds and the literature. No noise.
Subscribe & earn 500 pointsCookies
We use strictly necessary cookies to run the store. With your consent we also use analytics (order attribution) and marketing (Omnisend) cookies. Read our Cookie Policy.
