Plain-spoken notes on the compounds we supply — what the literature shows, how to read a COA, and the protocols that protect your data. Cited, never hyped.
Nootropics
A plant alkaloid, a fragment-derived peptidomimetic, a curcumin descendant, a 150-year-old dye and a vitamin-B3 relative. The cognitive-enhancement conversation is not only about peptides…
Nootropics
Most nootropics people argue about online are small molecules. A quieter family is built from amino acids. A research-use-only field guide to the peptides…
Nootropics
Selank is a synthetic heptapeptide derived from the natural immune molecule tuftsin, developed in Russia and studied in animal models as an anxiolytic and…
Nootropics
Semax is a synthetic heptapeptide derived from a fragment of the stress hormone ACTH, developed in Russia and studied as a nootropic and neuroprotective…
In the news
In a few short years, peptides went from obscure lab reagents to the most-discussed molecules in longevity and biohacking culture. A look at why…
Bioregulators
A guide to the Russian peptide-bioregulator school: very short peptides, each tied to a tissue, proposed to influence gene expression. What the catalogue is,…
Bioregulators
A profile of the Russian gerontologist who spent decades arguing that peptides just a few amino acids long could tune the genome and slow…
Methods & QC
A vial without a Certificate of Analysis is a guess wearing a label. A COA is how “trust me” becomes “here are the numbers”…
Metabolic & longevity
5-Amino-1MQ is a small-molecule inhibitor of the enzyme NNMT, studied in cells and obese mice for its effects on the NAD+ and methylation economy…
Metabolic & longevity
Two synthetic peptides that are almost always studied as a pair: one mimics ghrelin, the other mimics GHRH. A research primer on how each…
Tissue repair
KPV is Lys-Pro-Val, the C-terminal tripeptide of alpha-MSH that preclinical work has studied for its outsized anti-inflammatory activity. A look at what the cell…
Metabolic & longevity
How metabolic research moved from a single receptor to two to three — and what each added hormone receptor changed in the preclinical and…
Occasional, considered notes on the compounds and the literature. No noise.
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