Plain-spoken notes on the compounds we supply — what the literature shows, how to read a COA, and the protocols that protect your data. Cited, never hyped.
Metabolic & longevity
NAD+ falls with age and an entire industry promises to refill it. But “raises NAD+” and “slows ageing” are two different claims — and…
Hormonal
Enclomiphene is the purified trans-isomer of clomiphene, a SERM studied for raising a man’s own testosterone by lifting estrogen’s brake on the brain. It…
Metabolic & longevity
MOTS-c is a 16-amino-acid peptide encoded inside the mitochondrial genome itself, studied as an exercise-responsive metabolic signal. The biology is genuinely striking — but…
Metabolic & longevity
A synthetic pan-agonist of the estrogen-related receptors, studied as an “exercise mimetic” that switches on the oxidative-metabolism programme a workout normally triggers. Here is…
Metabolic & longevity
Tesofensine (NS2330) is a small-molecule triple monoamine reuptake inhibitor that produced some of the largest weight-loss figures of the pre-GLP-1 era in human obesity…
Metabolic & longevity
AOD-9604 is a synthetic fragment of human growth hormone, engineered to keep a fat-metabolising signal while shedding the growth. It became a famous “fat-burning…
Metabolic & longevity
NAD+ is the redox coenzyme every cell uses to make energy and to fuel its sirtuins and PARPs — and its levels fall with…
Metabolic & longevity
NMN is a direct precursor of NAD+, the metabolic coenzyme that fades with age. It is the molecule the anti-ageing field bet on to…
Nootropics
A blue dye older than aspirin helped found the pharmaceutical industry and still treats a rare blood disorder. At low concentrations it is now…
Nootropics
J-147 is an experimental neuroprotective compound engineered at the Salk Institute from curcumin, the turmeric molecule the body destroys too fast to be a…
Nootropics
Dihexa is a metabolically stabilised peptidomimetic, derived from angiotensin IV, designed to drive the formation of new synapses through the HGF/c-Met growth system. Here…
Nootropics
A small beta-carboline alkaloid that, in animal models, appears to stimulate, protect and even regenerate dopaminergic neurons — from a chemical family that also…
Occasional, considered notes on the compounds and the literature. No noise.
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