The Research Journal

Peptide science, clearly referenced.

Independent, literature-backed explainers on research compounds — every claim cited to PubMed, every framing strictly research-use-only.

The Peptide Gray Market, Explained: How to Choose a Trustworthy Supplier
Methods & QC · Featured
The Peptide Gray Market, Explained: How to Choose a Trustworthy Supplier

Research peptides occupy a legal and commercial gray zone with its own economics. Understanding that structure — and demanding the right documents — is the best protection a laboratory buyer has.

Scientific desk8 min read
Endotoxins and Sterility: The COA Section Almost Nobody Reads
Methods & QC
Endotoxins and Sterility: The COA Section Almost Nobody Reads

A 99% purity figure tells you nothing about endotoxin load — and that blind spot is one of the quietest causes of irreproducible cell-culture and in-vitro research. Here is why the bacterial endotoxin test deserves a place on every certificate of analysis.

7 min
Peptide Stacks: The Logic, the Evidence, and the Marketing
Methods & QC
Peptide Stacks: The Logic, the Evidence, and the Marketing

Online forums present elaborate peptide “stacks” with the confidence of clinical protocols. The published literature tells a far humbler story — and the gap between the two is where the marketing lives.

8 min
Research Peptides in 2026: How the FDA and EMA Treat Them
Regulation
Research Peptides in 2026: How the FDA and EMA Treat Them

A neutral 2026 map of how the FDA, the EMA and the anti-doping world actually treat research peptides — and why “Research Use Only” is a defined legal frame, not a loophole.

7 min
Khavinson’s Peptide Bioregulators: A Field Guide to the “Cytogen” Catalogue (2026)
Bioregulators
Khavinson’s Peptide Bioregulators: A Field Guide to the “Cytogen” Catalogue (2026)

A Soviet-born research programme assigned a short peptide to nearly every organ in the body. Here is the map of the “cytogen” catalogue—and an honest reckoning with the state of the evidence in 2026.

7 min
The IGF-1 / mTOR Dilemma: Muscle Versus Longevity
Metabolic & longevity
The IGF-1 / mTOR Dilemma: Muscle Versus Longevity

The same growth signalling that builds muscle is the one whose quieting extends lifespan in animals. An honest look at a paradox biology has not cleanly resolved in humans — and at the research tools used to probe it.

7 min
Melanocortins: From Vyleesi to Melanotan II
Sexual health
Melanocortins: From Vyleesi to Melanotan II

Tanning and arousal run through the same family of receptors. That single fact explains both Melanotan II’s appeal and its downfall — and why pharmacology eventually chose selectivity over the catch-all peptide.

6 min
Copper Peptides Compared: GHK-Cu vs AHK-Cu
Skin & matrix
Copper Peptides Compared: GHK-Cu vs AHK-Cu

Two copper-carrying tripeptides sit side by side in the catalogue—one with a half-century of multi-group science behind it, the other with a thinner, mostly cosmetic-industry record. This is the honest head-to-head the marketing rarely offers.

6 min
“Leaky Gut” Examined: Zonulin, Tight Junctions and Larazotide
Gut
“Leaky Gut” Examined: Zonulin, Tight Junctions and Larazotide

A myth-versus-mechanism fact-check on one of wellness's most abused phrases. The intestinal barrier is real biology; “leaky gut” as a catch-all diagnosis is not — and the one peptide that put the hypothesis to a large human test tells a sobering story.

7 min
What Is IGF-1 LR3? The Growth Factor Engineered to Outlast Its Own Brakes
Tissue repair
What Is IGF-1 LR3? The Growth Factor Engineered to Outlast Its Own Brakes

IGF-1 LR3 is a re-engineered version of insulin-like growth factor 1, redesigned to slip past the binding proteins that normally rein it in. Here is what the chemistry actually does, what the preclinical literature shows, and why the honest reading carries a serious caveat.

9 min