Lyophilised · ≥99% (HPLC) ·
Supplied lyophilised. Reconstitution typically uses bacteriostatic water.
TB-500 is the synthetic active fragment derived from the actin-binding domain of Thymosin beta-4, a 43-amino-acid regenerative protein, studied in cell-migration, angiogenesis and tissue-repair models. Supplied as a sterile lyophilised acetylated peptide at ≥99% purity by reversed-phase HPLC in a 10 mg vial. For laboratory research use only; not for human or veterinary use.
Corresponding to the active region of a peptide the body produces naturally, TB-500 is the synthetic, bioavailable fragment derived from thymosin β4 — a 43-residue actin-binding peptide expressed across human tissues. It is one of the most widely studied molecules in cell-migration and tissue-repair research, valued in the laboratory for its solubility and its link to a well-characterised parent protein.
A fragment of a developmental peptide. Thymosin β4 is a naturally occurring actin-sequestering peptide whose expression has been mapped across many human organs during development (Faa et al., 2024). TB-500 reproduces the functional core associated with this molecule, allowing researchers to probe thymosin β4 biology in experimental systems where the larger native peptide is harder to work with.
What the research explores. Rather than a single pathway, thymosin β4 and its fragments are investigated across several intersecting themes:
The findings outlined here come from in-vitro and animal studies; they characterise biological activity under laboratory conditions and do not establish efficacy or safety in humans. Full citations are listed under the Scientific References tab.
Physicochemical profile. CAS No. 77591-33-4 · Molecular formula C212H350N56O78S · Molecular weight 4963.44 g/mol · Sequence Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser · Appearance: white lyophilized powder · Solubility: soluble in water at 1 mg/mL.
Specification & quality. Each individually sealed vial contains 10 mg of TB-500 as a white lyophilized powder at ≥99% purity by HPLC. Every batch is third-party tested, and a Certificate of Analysis (COA) is available. Store at −20 °C, protected from light and moisture; shelf life 24 months from the manufacture date.
This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.
Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.
Certificate of Analysis — lot-specific COA ships with every order and is available on request.
Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.
References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.
TB-500 is a synthetic peptide based on thymosin beta-4, a 43-residue actin-binding peptide the body expresses across many tissues. It is widely studied in regenerative, cell-migration and tissue-repair research. Condor supplies it strictly as a Research Use Only reference compound for in vitro and animal studies, not for human or veterinary use.
TB-500 is a large peptide (43 residues, MW ~4963) based on thymosin beta-4, studied for actin binding and cell migration. BPC-157 is a small 15-amino-acid peptide derived from a gastric protein, studied for cytoprotection. They act through different mechanisms, so both are used as distinct tissue-repair reagents. Research use only.
TB-500 is the full thymosin beta-4-based peptide (43 residues, 10 mg/vial). TB-500 (Frag) is the short N-terminal fragment Ac-Ser-Asp-Lys-Pro (the Ac-SDKP tetrapeptide, 2 mg/vial), a distinct active sequence cleaved from the parent. Choose the full peptide or the fragment depending on which sequence your research targets. Research use only.
This TB-500 is the full thymosin beta-4-based peptide: 43 residues, molecular formula C212H350N56O78S, MW 4963.44 (CAS 77591-33-4). The separately listed TB-500 (Frag) product is the short Ac-SDKP tetrapeptide. Identity and purity (>=99%) are confirmed by HPLC on each batch, documented in the lot Certificate of Analysis.
Yes. The TB-500 component in GLOW and KLOW is the same 10 mg full-length thymosin beta-4-based peptide as the standalone vial, co-formulated with other peptides rather than supplied alone. Choose the standalone to study TB-500 in isolation, or a blend to investigate it alongside BPC-157 and GHK-Cu. Research use only.
Yes. Condor Research supplies TB-500 strictly as a Research Use Only (in vitro) reference compound to professionals and institutions, not as a medicine, supplement or product for human or veterinary use. Buyers are responsible for confirming import legality in their own country. Questions: info@condorresearch.com.
Yes. Every TB-500 batch is tested by an independent third-party laboratory by HPLC for identity and purity (>=99%), with mass spectrometry confirmation of this large peptide, and ships with a lot-specific Certificate of Analysis. To request the COA before ordering, contact info@condorresearch.com.
For laboratory preparation, TB-500 is reconstituted in water (listed solubility 1 mg/mL); adding 10 mL of bacteriostatic water to the 10 mg vial gives 1 mg/mL. Store the sealed vial at -20C, protected from light; shelf life is 24 months. For in vitro and animal research only, never human or veterinary use.
Lyophilized TB-500 is stable for short room-temperature transit, so cold packs are generally not required for shipping; brief delivery times within Europe do not compromise the powder. On arrival, store the sealed vial at -20C, protected from light, for long-term stability. Questions: info@condorresearch.com.
If a vial arrives damaged or non-conforming, notify info@condorresearch.com ideally within 48 hours with photos, and a replacement, reshipment or store credit can be arranged. Each batch is independently HPLC-tested at >=99% with a Certificate of Analysis backing the stated purity. Sealed laboratory goods are otherwise final sale (B2B).
Cold-chain handling was respected end to end. Vials arrived sealed, labelled and intact. Documentation is the most thorough I've seen from an EU supplier.
Solubility and stability were as described. Knocked one star only because express shipping options are limited, but quality is not in question.
Third order with Condor. Batch-to-batch variation is minimal, which matters for our longitudinal work. The mono-labelled vials are easy to track.
No marketing fluff — just characterised material with paperwork. The data sheet and CAS matched our records precisely.
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