Lyophilised · ≥99% (HPLC) ·
Supplied lyophilised. Reconstitution typically uses bacteriostatic water.
TB-500 is synthetic full-length thymosin beta-4: the complete 43-amino-acid, N-terminally acetylated actin-sequestering protein (CAS 77591-33-4), studied in cell-migration, angiogenesis and tissue-repair models. Supplied as thymosin beta-4 acetate (the acetate salt), a sterile lyophilised peptide, at ≥99% purity by reversed-phase HPLC in a 10 mg vial. It is not the 7-residue Ac-LKKTETQ fragment, which Condor Research lists separately as TB-500 (Frag). For laboratory research use only; not for human or veterinary use.
Reproducing a peptide the body produces naturally, TB-500 here is the full synthetic sequence of thymosin β4 — a 43-residue actin-binding peptide expressed across human tissues. It is one of the most widely studied molecules in cell-migration and tissue-repair research, valued in the laboratory for its solubility and for matching the sequence of a well-characterised native protein.
The whole developmental peptide, not a fragment. Thymosin β4 is a naturally occurring actin-sequestering peptide whose expression has been mapped across many human organs during development (Faa et al., 2024). Because TB-500 carries the complete sequence — from the N-terminal Ac-SDKP region to the central actin-binding motif at residues 17–23 — it lets researchers study the intact molecule rather than isolated sub-sequences.
What the research explores. Rather than a single pathway, thymosin β4 — and, in some studies, peptides derived from it — is investigated across several intersecting themes:
The findings outlined here come from in-vitro and animal studies; they characterise biological activity under laboratory conditions and do not establish efficacy or safety in humans. Full citations are listed under the Scientific References tab.
Which “TB-500” is which. The name is used in the market for more than one molecule; sequence, mass and CAS number, not the trade name, identify what is in the vial.
| Condor Research product | Molecule | Sequence | Length | MW (g/mol) | CAS |
|---|---|---|---|---|---|
| TB-500 (Frag); TB-500 Capsules; the TB-500 in BPC-157 + TB-500, GLOW, KLOW and BPC-157 Arginate + TB-500 Capsules | Thymosin β4 fragment 17–23, N-acetylated | Ac-LKKTETQ | 7 aa | 889.0 | 885340-08-9 |
| TB-500 (10 mg vial) | Full-length thymosin β4 | Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES | 43 aa | 4963.44 | 77591-33-4 |
| Not listed by Condor Research | Thymosin β4 fragment 1–4 (goralatide) | Ac-SDKP | 4 aa | 487.5 | 120081-14-3 |
Physicochemical profile. CAS No. 77591-33-4 · Molecular formula C212H350N56O78S · Molecular weight 4963.44 g/mol · Sequence Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser · Appearance: white lyophilized powder · Solubility: soluble in water at 1 mg/mL.
Specification & quality. Each individually sealed vial contains 10 mg of TB-500 as a white lyophilized powder at ≥99% purity by HPLC. Every batch is third-party tested, and a Certificate of Analysis (COA) is available. Store at −20 °C, protected from light and moisture; shelf life 24 months from the manufacture date.
This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.
Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.
Certificate of Analysis — lot-specific COA ships with every order and is available on request.
Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.
References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.
TB-500 is a synthetic peptide based on thymosin beta-4, a 43-residue actin-binding peptide the body expresses across many tissues. It is widely studied in regenerative, cell-migration and tissue-repair research. Condor supplies it strictly as a Research Use Only reference compound for in vitro and animal studies, not for human or veterinary use.
TB-500 is a large peptide (43 residues, MW ~4963) based on thymosin beta-4, studied for actin binding and cell migration. BPC-157 is a small 15-amino-acid peptide derived from a gastric protein, studied for cytoprotection. They act through different mechanisms, so both are used as distinct tissue-repair reagents. Research use only.
TB-500 is full-length synthetic thymosin beta-4 (43 residues, MW 4963.44, CAS 77591-33-4; 10 mg/vial). TB-500 (Frag) is Ac-LKKTETQ, the acetylated 7-residue sequence from residues 17–23 — the central actin-binding motif (MW 889.0, CAS 885340-08-9; 2 mg/vial). They are different molecules, not two strengths of one. Choose the full peptide or the fragment depending on whether your research targets the intact protein or that motif. Research use only.
This TB-500 is the full thymosin beta-4-based peptide: 43 residues, molecular formula C212H350N56O78S, MW 4963.44 (CAS 77591-33-4). The separately listed TB-500 (Frag) product is the 7-residue Ac-LKKTETQ fragment (thymosin beta-4 residues 17–23), and TB-500 Capsules contain that same fragment. Identity and purity (>=99%) are confirmed by HPLC on each batch, documented in the lot Certificate of Analysis.
No. The TB-500 component in GLOW, KLOW and the BPC-157 + TB-500 blend is the 7-residue fragment Ac-LKKTETQ (thymosin beta-4 residues 17–23, CAS 885340-08-9), the same molecule as TB-500 (Frag) — not the full-length 43-residue thymosin beta-4 in this 10 mg vial. Choose this standalone vial to study the intact protein, or a blend to investigate the fragment alongside BPC-157 and GHK-Cu. Research use only.
Yes. Condor Research supplies TB-500 strictly as a Research Use Only (in vitro) reference compound to professionals and institutions, not as a medicine, supplement or product for human or veterinary use. Buyers are responsible for confirming import legality in their own country. Questions: info@condorresearch.com.
Yes. Every TB-500 batch is tested by an independent third-party laboratory by HPLC for identity and purity (>=99%), with mass spectrometry confirmation of this large peptide, and ships with a lot-specific Certificate of Analysis. To request the COA before ordering, contact info@condorresearch.com.
For laboratory preparation, TB-500 is reconstituted in water (listed solubility 1 mg/mL); adding 10 mL of bacteriostatic water to the 10 mg vial gives 1 mg/mL. Store the sealed vial at -20C, protected from light; shelf life is 24 months. For in vitro and animal research only, never human or veterinary use.
Lyophilized TB-500 is stable for short room-temperature transit, so cold packs are generally not required for shipping; brief delivery times within Europe do not compromise the powder. On arrival, store the sealed vial at -20C, protected from light, for long-term stability. Questions: info@condorresearch.com.
If a vial arrives damaged or non-conforming, notify info@condorresearch.com ideally within 48 hours with photos, and a replacement, reshipment or store credit can be arranged. Each batch is independently HPLC-tested at >=99% with a Certificate of Analysis backing the stated purity. Sealed laboratory goods are otherwise final sale (B2B).
Condor Research supplies TB-500 directly, dispatched from our EU facility in Slovakia to the EU, EEA, UK and Switzerland. Deliveries to EU destinations clear no third-country customs, and shipping is calculated at checkout. Supplied strictly as a research-use-only reference material — not for human or veterinary use.
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