Lyophilised · ≥99% (HPLC) ·
Supplied lyophilised. Reconstitution typically uses bacteriostatic water.
When a cell needs to move, rebuild a wound edge, or sprout a new vessel, it first has to remodel its own internal scaffolding — and that scaffolding is actin. TB-500 is the synthetic counterpart of the active region of Thymosin β-4, a 43-amino-acid actin-sequestering peptide that sits at the heart of how cells reshape themselves during migration and repair. It has become a reference tool for laboratories probing the molecular choreography of tissue regeneration.
An actin-binding peptide drawn from a developmental regulator. Thymosin β-4 is one of the most abundant actin-binding proteins in many cell types, and its expression has been mapped across human organ development, marking it as a deeply conserved player in tissue formation (Faa et al., 2024). TB-500 reproduces the G-actin-binding motif responsible for much of that activity, which is why it is studied as a probe for cell motility, angiogenesis and regenerative signalling.
Beyond simple actin handling, the parent molecule has been framed as a candidate for anti-ageing and regenerative paradigms, with research mapping new mechanistic directions for the peptide family (Bock-Marquette et al., 2023).
What the research explores. Across cell-culture and animal systems, TB-500 has been investigated along several converging lines:
The activity described here is drawn from in-vitro and animal studies; it characterises biological behaviour in experimental models and does not establish efficacy or safety in humans. Full citations are listed under the Scientific References tab.
Physicochemical profile. CAS No. 77591-33-4 · Molecular formula C212H350N56O78S · Molecular weight 4963.44 g/mol · Sequence Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser (43 aa) · Appearance: White lyophilized powder · Solubility: Soluble in water.
Specification & quality. Each bottle contains 60 HPMC (vegan) capsules, each providing 500mcg of TB-500 at ≥99% (HPLC). Encapsulated — no reconstitution required. Every batch is independently third-party tested, and a Certificate of Analysis (COA) is available. Store at -20°C, protect from light and moisture; shelf life 24 months from the manufacture date. EU warehoused.
This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.
Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.
Certificate of Analysis — lot-specific COA ships with every order and is available on request.
Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.
References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.
TB-500 is the synthetic version of the active region of Thymosin β-4, a 43-amino-acid actin-sequestering peptide studied for its role in cell migration, angiogenesis and tissue-repair signalling. Its biology has been examined across cardiac, corneal and regenerative models (Maar et al., 2025). Condor Research supplies it strictly as a Research Use Only reference compound for in vitro and animal studies, not for human or veterinary use.
TB-500 is a 43-residue thymosin β-4 fragment studied primarily as an actin-binding peptide governing cell motility and angiogenesis, whereas BPC-157 is a 15-residue gastric pentadecapeptide studied around cytoprotection and the nitric-oxide system. They sit in different mechanistic classes and address different research questions about tissue dynamics. Both are supplied strictly as research-use-only reference compounds, not for human or veterinary use.
No. Thymosin β-4 is the full 43-residue protein and one of the most abundant actin-binding molecules in many cells, with expression mapped across human organ development (Faa et al., 2024). TB-500 reproduces the active actin-binding region of that protein, making it a focused tool for studying the same pathways. Both are handled only as research-use-only reference materials, never for human or veterinary use.
TB-500 is studied around actin regulation, cell migration and angiogenesis, while KPV is a melanocortin-derived tripeptide studied chiefly for anti-inflammatory signalling in intestinal and dermal models. They illuminate different stages of the tissue-response question — structural remodelling versus inflammatory tone. Each is offered solely as a Research Use Only reference compound, not for human or veterinary use.
Yes. Condor Research supplies TB-500 strictly as a Research Use Only reference compound to professionals and institutions, not as a medicine, supplement or product for human or veterinary use. Buyers are responsible for confirming import legality in their own country. Questions: info@condorresearch.com.
The capsule is simply a pre-weighed solid format: 500mcg of TB-500 sealed in an HPMC (vegan) shell so each unit holds a precise, handling-ready quantity. This removes weighing steps at the bench and requires no reconstitution. The format is a laboratory convenience only and does not imply or permit human or veterinary consumption — for research use only.
No. The peptide is already encapsulated as a pre-measured solid, so no reconstitution is required for handling. Researchers prepare working solutions according to their own validated experimental protocols. The capsule is a laboratory format only and is not intended for human or veterinary use.
Each bottle contains 60 HPMC (vegan) capsules, with 500mcg of TB-500 per capsule at ≥99% (HPLC) purity. Every batch is independently third-party tested and a Certificate of Analysis is available on request. This specification describes a research reference material, not a product for human or veterinary use.
TB-500 has CAS No. 77591-33-4, molecular formula C212H350N56O78S and a molecular weight of 4963.44 g/mol. It is a 43-amino-acid acetylated peptide supplied as a white lyophilized powder, soluble in water. These values are provided for laboratory characterisation and research use only.
Yes. Every TB-500 batch is tested by an independent third-party laboratory by HPLC for identity and purity (≥99%), and each lot ships with a lot-specific Certificate of Analysis. To request the COA for your batch, contact info@condorresearch.com. This documentation supports research use only, not human or veterinary application.
Store at -20°C, protected from light and moisture, to preserve peptide integrity over the stated 24-month shelf life from the manufacture date. Stock is EU warehoused for reliable regional supply. For laboratory research use only. Not for human or veterinary use.
No marketing fluff — just characterised material with paperwork. The data sheet and CAS matched our records precisely.
Lyophilised cake was uniform and dissolved fully. Would appreciate a digital COA portal, but the PDF on request worked fine.
Identity by MS confirmed in our facility. Communication around storage and handling was precise and professional.
Reconstitution was clean with no visible particulates. The lot-specific COA matched the assay we ran in-house — purity is exactly as stated.
We verify every incoming compound by HPLC; this batch came back within tolerance of the certificate. Dispatch from the EU warehouse was quick.
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