Plain-spoken notes on the compounds we supply — what the literature shows, how to read a COA, and the protocols that protect your data. Cited, never hyped.
Metabolic & longevity
Cagrilintide (AM833) is a long-acting amylin analogue and dual amylin/calcitonin receptor agonist. Its chemistry, receptor pharmacology, and trial evidence, RUO.
Metabolic & longevity
Humanin is a 24-amino-acid mitochondrial-derived peptide encoded in the 16S rRNA region, studied in ageing, apoptosis and metabolic biology. RUO overview.
Metabolic & longevity
Adipotide (FTPP / Prohibitin-TP01) is a chimeric peptidomimetic studied for targeting white-fat blood vessels. What the primate and mouse data actually show — RUO.
Metabolic & longevity
FOXO4-DRI is a D-retro-inverso senolytic peptide that disrupted the FOXO4-p53 interaction and cleared senescent cells in aged mice. What the research actually shows.
Metabolic & longevity
SLU-PP-915 is a synthetic, orally bioavailable pan-ERR agonist. What the mouse and in-vitro literature actually shows, and where the evidence is still thin.
Metabolic & longevity
A small molecule made untrained mice run dramatically further. Two decades and several large human trials later, acadesine's record is a study in how…
Metabolic & longevity
A naturally occurring polyamine that induces autophagy from yeast to mice, backed by striking mortality epidemiology — and undercut by randomised human trials that…
Metabolic & longevity
Elamipretide is the most clinically advanced cardiolipin-targeting tetrapeptide ever tested — now an approved Barth-syndrome drug, yet with a trial record that is the…
Metabolic & longevity
Most research peptides suffer from thin, animal-only data. This GLP-1 receptor agonist has the opposite problem — and the gap between a licensed medicine…
Metabolic & longevity
Tirzepatide beat semaglutide head-to-head on weight loss in a randomised trial. Here is what the human data actually establish — and the hard line…
Metabolic & longevity
The same growth signalling that builds muscle is the one whose quieting extends lifespan in animals. An honest look at a paradox biology has…
Metabolic & longevity
MOTS-c is a 16-amino-acid peptide encoded inside the mitochondrial genome itself, studied as an exercise-responsive metabolic signal. The biology is genuinely striking — but…
Occasional, considered notes on the compounds and the literature. No noise.
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