Plain-spoken notes on the compounds we supply — what the literature shows, how to read a COA, and the protocols that protect your data. Cited, never hyped.
Bioregulators
A guide to the Russian peptide-bioregulator school: very short peptides, each tied to a tissue, proposed to influence gene expression. What the catalogue is,…
Methods & QC
A vial without a Certificate of Analysis is a guess wearing a label. A COA is how “trust me” becomes “here are the numbers”…
Metabolic & longevity
5-Amino-1MQ is a small-molecule inhibitor of the enzyme NNMT, studied in cells and obese mice for its effects on the NAD+ and methylation economy…
Metabolic & longevity
Two synthetic peptides that are almost always studied as a pair: one mimics ghrelin, the other mimics GHRH. A research primer on how each…
Tissue repair
KPV is Lys-Pro-Val, the C-terminal tripeptide of alpha-MSH that preclinical work has studied for its outsized anti-inflammatory activity. A look at what the cell…
Metabolic & longevity
How metabolic research moved from a single receptor to two to three — and what each added hormone receptor changed in the preclinical and…
In the news
On 20 April 2026, one of the world's biggest podcasts told millions that Big Pharma is hiding a powerful peptide. We checked the science,…
Metabolic & longevity
Epitalon evidence census: 165 PubMed records read one by one, 73-93% from one lineage, 3 human studies, 0 trials located, open data and code.…
Regulation
On 1 June 2026 the European Medicines Agency published its first rulebook for manufacturing synthetic-peptide medicines. Here is what it actually says, what it…
Metabolic & longevity
Retatrutide (LY3437943) is a single engineered peptide built to pull three metabolic levers at once. Here is what the science actually shows — and…
Tissue repair
TB-500 is a synthetic version of thymosin β4, a 43-residue protein that helps build and rebuild tissue across the body. Here is what the…
In the news
On 1 June 2026, Huberman Lab spent a full episode on peptides. It was more careful than most of the internet. Here is what…
Occasional, considered notes on the compounds and the literature. No noise.
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