Lyophilised · ≥99% (HPLC) ·
Supplied lyophilised. Reconstitution typically uses bacteriostatic water.
Thymosin Alpha-1 (Tα1) is a synthetic 28-amino-acid peptide originally isolated from thymosin fraction 5 of bovine thymus, studied extensively in immunomodulation, dendritic cell maturation, and T-cell signalling research. CAS 62304-98-7; sequence Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH; molecular weight 3108.36 g/mol; supplied lyophilised at ≥99% purity by HPLC. For laboratory research use only; not for human or veterinary use.
First isolated from a fraction of calf thymus that restored immune competence, Thymosin Alpha-1 is a synthetic 28-amino-acid acetylated peptide identical to a naturally occurring thymic hormone. As a central immunomodulator, it has become one of the most extensively investigated peptides in the study of host defence, inflammation, and immune homeostasis.
A messenger from the immune system's training ground. The thymus orchestrates the maturation of T cells, and Thymosin Alpha-1 is one of the signalling peptides it produces. Research established that the molecule helps tune the balance of immune responses — promoting T-cell differentiation and modulating innate and adaptive arms alike — which positioned it as a versatile experimental tool for probing immune regulation (King et al., 2016; Garaci et al., 2024).
What the research explores. The peptide spans a remarkably broad investigational landscape:
All such findings originate from in vitro, animal, and clinical research; no human-use conclusions are supported by this listing. Full citations are listed under the Scientific References tab.
Physicochemical profile. CAS 62304-98-7 · Molecular formula C₁₂₉H₂₁₅N₃₃O₅₅ · Molecular weight 3108.3 · Sequence Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn · Appearance: white lyophilized powder · Solubility: soluble in water.
Specification & quality. Each individually sealed vial contains 10 mg of Thymosin Alpha-1 as a white lyophilized powder of ≥99% purity by HPLC. Every batch is third-party tested, with a Certificate of Analysis (COA) available. Store at −20 °C, protected from light and moisture. Shelf life: 24 months from the manufacture date.
This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.
Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.
Certificate of Analysis — lot-specific COA ships with every order and is available on request.
Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.
References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.
Thymosin Alpha-1 is a synthetic 28-amino-acid acetylated peptide identical to a naturally occurring thymic hormone, first isolated from a thymus fraction that restored immune competence. It is studied chiefly in immune-modulation research. Condor Research supplies it as a 10 mg vial, third-party tested to ≥99% purity by HPLC, strictly for in-vitro research use.
Despite the shared "thymosin" name, they are unrelated peptides with different research areas. Thymosin Alpha-1 is a 28-residue acetylated thymic peptide studied in immune modulation. TB-500 is the active fragment of thymosin β4, a 43-residue actin-binding peptide studied in tissue repair and regeneration. Different sequences, different focus. Both are Research Use Only materials.
The names are misleading: thymosin α1 and thymosin β4 belong to separate peptide families. Thymosin Alpha-1 (28 residues, acetylated) is an immune-focused research peptide; TB-500, derived from thymosin β4 (43 residues), is studied for actin binding and tissue repair. They are not variants of one molecule. Both are supplied strictly for in-vitro use.
Both feature in immunity research but act differently. Thymosin Alpha-1 is a 28-residue thymic peptide studied as an immune modulator. LL-37 is the human cathelicidin-derived antimicrobial peptide, studied for direct antimicrobial activity in innate immunity. So one is broadly immunomodulatory and the other antimicrobial. Both are offered as Research Use Only reference compounds.
Both appear in immune-related research but are structurally and mechanistically distinct. Thymosin Alpha-1 is a 28-residue acetylated thymic peptide studied as an immune modulator. KPV is a three-residue α-MSH C-terminal fragment (Lys-Pro-Val) studied for anti-inflammatory activity. Different size, origin and focus. Both are supplied strictly as in-vitro research materials.
Yes — the N-terminal acetyl group is integral to the molecule's identity and is reflected in the listed acetylated sequence and molecular weight (3108.3). Each lot is tested by an independent third-party laboratory, with identity and purity confirmed by HPLC and mass spec, certifying ≥99% purity. For the batch-specific COA, contact info@condorresearch.com.
Each lot ships with a batch-specific Certificate of Analysis from an independent third-party laboratory, with purity by HPLC certified to ≥99% and identity confirmed by mass spec, which captures synthesis-related impurities such as deletion sequences for a peptide of this length. For the full impurity breakdown on the current Thymosin Alpha-1 lot, request the COA at info@condorresearch.com.
Thymosin Alpha-1 is a water-soluble lyophilized powder, dissolved in a compatible aqueous diluent for in-vitro preparation, with volume chosen to reach the target analytical concentration from the 10 mg vial. Store the sealed vial at -20°C, protected from light (24-month shelf life). This is analytical preparation only; no human or veterinary dosing guidance is provided.
No — Thymosin Alpha-1 is supplied strictly as a Research Use Only (in vitro) reference material: not a medicine, supplement or medical device, and not for human or veterinary administration or consumption. Sales are restricted to professionals and institutions aged 18+. Buyers are responsible for confirming the legality of import in their own jurisdiction.
Lyophilised cake was uniform and dissolved fully. Would appreciate a digital COA portal, but the PDF on request worked fine.
Identity by MS confirmed in our facility. Communication around storage and handling was precise and professional.
Reconstitution was clean with no visible particulates. The lot-specific COA matched the assay we ran in-house — purity is exactly as stated.
We verify every incoming compound by HPLC; this batch came back within tolerance of the certificate. Dispatch from the EU warehouse was quick.
Cookies
We use strictly necessary cookies to run the store. With your consent we also use analytics (order attribution) and marketing (Omnisend) cookies. Read our Cookie Policy.
