Research use only · EU-warehoused · COA on every batch · HPLC ≥99% · Shipment 2–5 days
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Selank

Selank

Lyophilised · ≥99% (HPLC) ·

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Supplied lyophilised. Reconstitution typically uses bacteriostatic water.

How to reconstitute Selank — stock calculator
Independently third-party tested · COA on every batch · 48h EU dispatch
[01]

Overview

Selank is a synthetic heptapeptide analogue of the immunopeptide tuftsin, developed in Russia and stabilised against enzymatic breakdown, studied as an anxiolytic and nootropic research peptide. CAS 129954-34-3; molecular formula C33H57N11O9; sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro; supplied lyophilised at ≥99% by HPLC. For laboratory research use only.

Derived from the immune-modulating fragment of the natural tetrapeptide tuftsin, Selank is a synthetic heptapeptide developed as a metabolically stabilized research analogue. By extending the parent Thr-Lys-Pro-Arg motif with a Pro-Gly-Pro tail, its designers produced a molecule far more resistant to peptidase degradation, making it a durable probe for studying regulatory peptide signalling in the central nervous system.

A peptide engineered from the body's own regulatory fragment. Tuftsin is a naturally occurring immunoactive peptide cleaved from immunoglobulin G. Russian peptide chemists at the Institute of Molecular Genetics built Selank around its core sequence specifically to slow enzymatic breakdown and to interrogate how short regulatory peptides influence anxiety-related circuits, neurotransmission and the endogenous opioid system. The result is one of the most studied members of the synthetic regulatory-peptide class.

What the research explores. The experimental literature on Selank concentrates on neuropharmacology in cellular and rodent models:

  • Anxiolytic-type signalling — mechanistic reviews have mapped the molecular aspects of its biological activity as a peptide anxiolytic in experimental systems (Vyunova et al., 2018).
  • Enzyme and peptidase interaction — early work showed it inhibits enkephalin-degrading enzymes, a route by which it may prolong endogenous peptide signalling (Kost et al., 2001).
  • Synaptic and hippocampal activity — electrophysiological studies have examined its effect on spontaneous synaptic activity in rat hippocampal neurons (Povarov et al., 2017).
  • Neuroprotection models — as a tuftsin analogue it has been assessed in ethanol-induced injury paradigms in animals (Kolik et al., 2019).

All such observations stem from in‑vitro and animal research and imply nothing about effects in humans. Full citations are listed under the Scientific References tab.

Physicochemical profile. CAS 129954-34-3 · Molecular formula C33H57N11O9 · Molecular weight 751.87 g/mol · Sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro · Appearance white lyophilized powder · Soluble in water.

Specification & quality. Each individually sealed vial contains 10 mg of Selank at ≥99% purity by HPLC. Every batch is third-party tested, with a Certificate of Analysis (COA) available. Store at −20 °C, protected from light and moisture.

This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.

Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.

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Quality & COA

Certificate of Analysis
Lot-specific COA with every order

Certificate of Analysis — lot-specific COA ships with every order and is available on request.

Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.

HPLC purity
≥99% (HPLC)
Method
HPLC + MS
Endotoxin
Reported
[02]

Data Sheet

CAS number129954-34-3
Molecular formulaC33H57N11O9
Molecular weight751.87
SequenceThr-Lys-Pro-Arg-Pro-Gly-Pro
Purity≥99% (HPLC)
Physical formWhite lyophilized powder
Quantity10mg/vial
SolubilitySoluble in water
StorageStore at -20°C, protect from light
ReconstitutionReconstitute with bacteriostatic water or sterile saline.
Shelf life24 months from manufacture date
OriginEU · Slovakia
ClassificationResearch use only
[03]

Scientific References

01 Liapina LA, Pastorova VE, Obergan TIu, Samonina GE, Ashmarin IP, Miasoedov NF [Comparison of anticoagulant effects of regulatory proline-containing oligopeptides. Specificity of glyprolines, semax, and selank and potential of their practical application]. Izvestiia Akademii nauk. Seriia biologicheskaia. 2006;(2):193-203. PMID: 16634437. PubMed 02 Kost NV, Sokolov OIu, Gabaeva MV, Grivennikov IA, Andreeva LA, Miasoedov NF et al. [Semax and selank inhibit the enkephalin-degrading enzymes from human serum]]. Bioorganicheskaia khimiia. 2001;27(3):180-3. PMID: 11443939. doi:10.1023/a:1011373002885. PubMed 03 Zozulya AA, Kost NV, Yu Sokolov O, Gabaeva MV, Grivennikov IA, Andreeva LN et al. The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity. Bulletin of experimental biology and medicine. 2001;131(4):315-7. PMID: 11550013. doi:10.1023/a:1017979514274. PubMed 04 Konstantinopolsky MA, Chernyakova IV, Kolik LG Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats. Bulletin of experimental biology and medicine. 2022;173(6):730-733. PMID: 36322304. doi:10.1007/s10517-022-05624-x. PubMed 05 Doyno CR, White CM Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank. Journal of clinical pharmacology. 2021;61 Suppl 2:S114-S128. PMID: 34396551. doi:10.1002/jcph.1922. PubMed 06 Leonidovna YA, Aleksandrovna SM, Aleksandrovna TA, Aleksandrovna BO, Fedorovich MN, Aleksandrovna AL The Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress. Current reviews in clinical and experimental pharmacology. 2021;16(2):162-167. PMID: 32621722. doi:10.2174/1574884715666200704152810. PubMed 07 Mukhina AY, Mishina ES, Bobyntsev II, Medvedeva OA, Svishcheva MV, Kalutskii PV et al. Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank. Bulletin of experimental biology and medicine. 2020;169(2):281-285. PMID: 32651826. doi:10.1007/s10517-020-04868-9. PubMed 08 Panikratova YR, Lebedeva IS, Sokolov OY, Rumshiskaya AD, Kupriyanov DA, Kost NV et al. Functional Connectomic Approach to Studying Selank and Semax Effects. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 2020;490(1):9-11. PMID: 32342318. doi:10.1134/S001249662001007X. PubMed 09 Kolik LG, Nadorova AV, Antipova TA, Kruglov SV, Kudrin VS, Durnev AD Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. Bulletin of experimental biology and medicine. 2019;167(5):641-644. PMID: 31625062. doi:10.1007/s10517-019-04588-9. PubMed 10 Fomenko EV, Bobyntsev II, Ivanov AV, Belykh AE, Andreeva LA, Myasoedov NF Effect of Selank on Morphological Parameters of Rat Liver in Chronic Foot-Shock Stress. Bulletin of experimental biology and medicine. 2019;167(2):293-296. PMID: 31243679. doi:10.1007/s10517-019-04512-1. PubMed 11 Mukhina AY, Medvedeva OA, Svishcheva MV, Shevchenko AV, Efremova NN, Bobyntsev II et al. State of Colon Microbiota in Rats during Chronic Restraint Stress and Selank Treatment. Bulletin of experimental biology and medicine. 2019;167(2):226-228. PMID: 31236882. doi:10.1007/s10517-019-04496-y. PubMed 12 Vyunova TV, Andreeva L, Shevchenko K, Myasoedov N Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity. Protein and peptide letters. 2018;25(10):914-923. PMID: 30255741. doi:10.2174/0929866525666180925144642. PubMed 13 Fomenko EV, Bobyntsev II, Kryukov AA, Ivanov AV, Andreeva LA, Myasoedov NF Effect of Selank on Functional State of Rat Hepatocytes under Conditions of Restraint Stress. Bulletin of experimental biology and medicine. 2017;163(4):415-418. PMID: 28853100. doi:10.1007/s10517-017-3817-8. PubMed 14 Slominsky PA, Shadrina MI, Kolomin TA, Stavrovskaya AV, Filatova EV, Andreeva LA et al. Peptides semax and selank affect the behavior of rats with 6-OHDA induced PD-like parkinsonism. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 2017;474(1):106-109. PMID: 28702721. doi:10.1134/S0012496617030048. PubMed 15 Povarov IS, Kondratenko RV, Derevyagin VI, Myasoedov NF, Skrebitsky VG Effect of Selank on Spontaneous Synaptic Activity of Rat Hippocampal CA1 Neurons. Bulletin of experimental biology and medicine. 2017;162(5):640-642. PMID: 28361410. doi:10.1007/s10517-017-3676-3. PubMed

References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.

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FAQ

Selank is a synthetic heptapeptide developed as a metabolically stabilized research analogue of the immune-modulating fragment of the natural tetrapeptide tuftsin. Its sequence is Thr-Lys-Pro-Arg-Pro-Gly-Pro. Condor Research supplies it as a 10 mg lyophilized vial at ≥99% HPLC purity, strictly as a research-use-only reference material for in-vitro laboratory study.

Selank and Semax are distinct synthetic heptapeptides with different origins. Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derives from the immune peptide tuftsin and is studied in anxiolytic-focused research. Semax (Met-Glu-His-Phe-Pro-Gly-Pro) derives from the ACTH(4-10) fragment and is investigated as a nootropic research model. Both are sold as separate ≥99% HPLC, research-use-only reference compounds.

Selank and DSIP are different neuropeptides studied in different contexts. Selank is a tuftsin-derived heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) investigated in anxiolytic-focused research. DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide studied in sleep and neuroregulatory research. Both are supplied as separate 10 mg vials at ≥99% HPLC purity, for research use only.

That depends on your study design. A standalone 10 mg Selank vial lets you set its concentration independently, while the co-formulated Semax + Selank blend (10 mg + 10 mg) supplies both heptapeptides in one vial for studies examining them together. All formats are research-use-only reference materials. For pricing comparison, contact info@condorresearch.com.

The two share a heptapeptide length but come from unrelated parent molecules. Selank is engineered from tuftsin, an immune-derived peptide, giving it a Thr-Lys-Pro-Arg-Pro-Gly-Pro sequence. Semax is built from the ACTH(4-10) corticotropin fragment. Their different origins are why they are studied as distinct research tools rather than interchangeable neuropeptide analogues.

Both are short synthetic peptides, but their research targets differ entirely. Selank is a tuftsin-derived heptapeptide studied in anxiolytic and neuropeptide research. Kisspeptin-10 is a 10-amino-acid fragment of the KISS1-encoded kisspeptin family, investigated at the top of the reproductive hormone cascade. Each is supplied as a separate ≥99% HPLC, research-use-only reference peptide.

Yes. Selank is supplied strictly for laboratory research use only (in vitro). It is not a medicine, food, supplement, cosmetic, or medical device, and is not for human or veterinary use, administration, or consumption. Condor Research provides no human-use dosing or protocols. Purchase is restricted to qualified professionals and institutions aged 18 or over.

For analytical laboratory preparation only, Selank is water-soluble and can be reconstituted with a sterile aqueous diluent; the volume chosen sets the working concentration. Store the sealed lyophilized vial at -20°C, protected from light, with a 24-month shelf life from manufacture. This is laboratory handling information, not guidance for any human or animal use.

Yes. Each Selank lot is tested by an independent third-party laboratory by HPLC for identity and purity, with mass spectrometry confirmation, and ships against a batch-specific Certificate of Analysis (COA) verifying ≥99% purity. To request the COA for the current lot before ordering, contact info@condorresearch.com.

Each Selank vial contains 10 mg of lyophilized peptide at ≥99% HPLC purity, supplied as a research-use-only reference material. The stated mass is an analytical reference quantity, not a dose. Vial fill and identity are verified by independent third-party testing and documented on the lot's Certificate of Analysis.

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Reviews

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4.7
74 verified reviews
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Apr 2026
Reproducible across batches

Third order with Condor. Batch-to-batch variation is minimal, which matters for our longitudinal work. The mono-labelled vials are easy to track.

Dr. R. Costa · Academic lab · PT Verified purchase
Mar 2026
Exactly what research needs

No marketing fluff — just characterised material with paperwork. The data sheet and CAS matched our records precisely.

J. Meijer · Biotech R&D · NL Verified purchase
Mar 2026
High purity, clear labelling

Lyophilised cake was uniform and dissolved fully. Would appreciate a digital COA portal, but the PDF on request worked fine.

Dr. A. Bianchi · University · IT Verified purchase
Feb 2026
Trustworthy supplier

Identity by MS confirmed in our facility. Communication around storage and handling was precise and professional.

K. Wójcik · Research group · PL Verified purchase

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