Lyophilised · ≥98% (HPLC) ·
Supplied lyophilised. Reconstitution typically uses bacteriostatic water.
Enclomiphene (trans-clomiphene) is a non-steroidal selective estrogen receptor modulator (SERM) and the active geometric isomer of clomiphene citrate; CAS 15690-57-0 (free base); molecular formula C₂₆H₂₈ClNO; molecular weight 406.0 g/mol. It acts as an estrogen receptor antagonist at the hypothalamic level, studied for its role in modulating the HPG axis in male endocrine research models. Supplied as encapsulated compound at ≥99% purity by HPLC. For laboratory research use only; not for human or veterinary use.
Clomiphene has long been a textbook example of a molecule that is really two molecules — a mixture of geometric isomers with opposing pharmacology. Enclomiphene is the purified trans-isomer of that pair: a selective estrogen-receptor modulator (SERM) isolated as a single, well-defined chemical entity, and a compound that has drawn sustained interest as a research probe of the hypothalamic-pituitary-gonadal (HPG) axis.
A SERM with a defined isomeric identity. As an estrogen-receptor antagonist at the level of the hypothalamus and pituitary, enclomiphene is studied for how SERM activity modulates gonadotropin signalling in experimental endocrine models (Hill et al., 2009; Rodriguez et al., 2016). Its distinct trans/cis isomeric chemistry — separating it from the cis-isomer zuclomiphene — remains an active subject of physicochemical characterisation (Trubert et al., 2025).
What the research explores. Across cell-culture and animal systems, enclomiphene has been investigated along several converging lines:
The activity described here is drawn from in-vitro and animal studies; it characterises biological behaviour in experimental models and does not establish efficacy or safety in humans. Full citations are listed under the Scientific References tab.
Physicochemical profile. CAS No. 15690-57-0 · Molecular formula C26H28ClNO · Molecular weight 405.96 g/mol · Appearance: White to off-white powder · Solubility: Soluble in DMSO and ethanol.
Specification & quality. Each bottle contains 60 HPMC (vegan) capsules, each providing 12.5mg of Enclomiphene at ≥98% (HPLC). Encapsulated — no reconstitution required. Every batch is independently third-party tested, and a Certificate of Analysis (COA) is available. Store at room temperature, protect from light and moisture; shelf life 24 months from the manufacture date. EU warehoused.
This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.
Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.
Certificate of Analysis — lot-specific COA ships with every order and is available on request.
Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.
References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.
Enclomiphene is the trans-isomer of clomiphene, a selective estrogen-receptor modulator (SERM) that acts as an estrogen-receptor antagonist, studied in hypothalamic-pituitary-gonadal (HPG) axis and gonadotropin-regulation models (Hill et al., 2009). It is used as a research probe in endocrine experimental systems. Condor Research supplies it strictly as a Research Use Only reference compound, never for human or veterinary use, and it is geo-restricted at checkout.
Clomiphene is a mixture of two geometric isomers, whereas enclomiphene is the purified trans-isomer isolated as a single chemical entity, separated from the cis-isomer (zuclomiphene). The two have distinct physicochemical and pharmacological profiles, which is an active subject of characterisation research (Trubert et al., 2025; Thomas et al., 2023). Both are supplied only as research-use-only reference compounds for in vitro and animal studies.
SERMs are a class of compounds that modulate estrogen-receptor signalling in a tissue-selective way, and enclomiphene is distinguished by its antagonist activity at the hypothalamic-pituitary level in HPG-axis research models (Tienforti et al., 2023). It serves as a defined single-isomer reference within that class for endocrine-signalling questions. It is offered strictly for laboratory research use only, not for human or veterinary use.
They are unrelated chemically and mechanistically. Enclomiphene is a SERM studied in estrogen-receptor and HPG-axis models (Hill et al., 2009), while Tesofensine is a triple monoamine reuptake inhibitor studied in CNS and energy-balance models. They address entirely different research questions and only share that both are geo-restricted at checkout. Both are supplied as research-use-only reference compounds.
Enclomiphene availability is limited by region because its regulatory status varies between jurisdictions, so checkout applies geo-restriction and the buyer is responsible for verifying that import of this Research Use Only reference compound is permitted where they are located. It is supplied under a strict RUO framework, never as a medicine, supplement or product for human or veterinary use. For eligibility questions, contact info@condorresearch.com.
Yes. Condor Research supplies Enclomiphene strictly as a Research Use Only reference compound to professionals and institutions, not as a medicine, supplement or product for human or veterinary use. Because it is geo-restricted, buyers are responsible for confirming import legality in their own country before ordering. Questions: info@condorresearch.com.
The capsule is a pre-weighed solid format that standardises the quantity of reference compound per unit, simplifying bench handling and inventory for laboratory work. Each is an HPMC (vegan) capsule containing the powder — no reconstitution is required, and the format does not imply or permit any form of consumption. For laboratory research use only. Not for human or veterinary use.
Each bottle contains 60 HPMC (vegan) capsules, with 12.5mg of Enclomiphene per capsule at ≥98% HPLC purity, and every batch is independently third-party tested. The per-capsule figure denotes only the pre-weighed quantity of reference compound for laboratory measurement — this product is for research use only and not for human or veterinary use, ingestion, or diagnostic application.
Enclomiphene has CAS No. 15690-57-0, a molecular formula of C26H28ClNO and a molecular weight of 405.96 g/mol. It presents as a white to off-white powder, soluble in DMSO and ethanol. These specifications are provided for laboratory identification and research use only.
Yes. Every Enclomiphene batch is tested by an independent third-party laboratory by HPLC for identity and purity (≥98%), and each lot ships with a lot-specific Certificate of Analysis. To request the COA for your batch, contact info@condorresearch.com. The material is supplied strictly for research use only.
Reconstitution was clean with no visible particulates. The lot-specific COA matched the assay we ran in-house — purity is exactly as stated.
We verify every incoming compound by HPLC; this batch came back within tolerance of the certificate. Dispatch from the EU warehouse was quick.
Cold-chain handling was respected end to end. Vials arrived sealed, labelled and intact. Documentation is the most thorough I've seen from an EU supplier.
Solubility and stability were as described. Knocked one star only because express shipping options are limited, but quality is not in question.
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