The Research Journal

Peptide science, clearly referenced.

Independent, literature-backed explainers on research compounds — every claim cited to PubMed, every framing strictly research-use-only.

What Are Ipamorelin and CJC-1295? The Two Doors to the Growth-Hormone Axis
Metabolic & longevity · Featured
What Are Ipamorelin and CJC-1295? The Two Doors to the Growth-Hormone Axis

Two synthetic peptides that are almost always studied as a pair: one mimics ghrelin, the other mimics GHRH. A research primer on how each knocks on the growth-hormone axis — and what the preclinical record actually shows.

Scientific desk6 min read
What Is 5-Amino-1MQ? The Small Molecule Built to Switch Off NNMT
Metabolic & longevity
What Is 5-Amino-1MQ? The Small Molecule Built to Switch Off NNMT

5-Amino-1MQ is a small-molecule inhibitor of the enzyme NNMT, studied in cells and obese mice for its effects on the NAD+ and methylation economy of fat tissue. Here is what the preclinical record actually shows — and where it stops.

6 min
How to Read a Certificate of Analysis (COA) for a Research Peptide
Methods & QC
How to Read a Certificate of Analysis (COA) for a Research Peptide

A vial without a Certificate of Analysis is a guess wearing a label. A COA is how “trust me” becomes “here are the numbers” — if you know how to read it. A practical, evergreen field guide for reproducible Research Use Only work.

10 min
The Diary of a CEO Peptide Episode, Fact-Checked
In the news
The Diary of a CEO Peptide Episode, Fact-Checked

On 20 April 2026, one of the world's biggest podcasts told millions that Big Pharma is hiding a powerful peptide. We checked the science, line by line: where the episode is right, where it is clickbait, and where the honest evidence simply runs out.

6 min
What is Epitalon? The microgram hypothesis and the dose the internet keeps getting wrong
Metabolic & longevity
What is Epitalon? The microgram hypothesis and the dose the internet keeps getting wrong

A four-letter peptide carries a decades-old case of mistaken identity. A 2026 re-examination argues the famous dose was never Epitalon's at all — and that the difference is a lesson in why what is in the vial matters more than the label on it.

7 min
The EMA’s First Synthetic-Peptide Guideline, Explained for European Researchers
Regulation
The EMA’s First Synthetic-Peptide Guideline, Explained for European Researchers

On 1 June 2026 the European Medicines Agency published its first rulebook for manufacturing synthetic-peptide medicines. Here is what it actually says, what it does not touch, and why it quietly raises the quality bar for everyone.

6 min
What Is TB-500? The Lab-Made Version of a Natural Repair Peptide
Tissue repair
What Is TB-500? The Lab-Made Version of a Natural Repair Peptide

TB-500 is a synthetic version of thymosin β4, a 43-residue protein that helps build and rebuild tissue across the body. Here is what the preclinical research actually shows — and where the human evidence runs thin.

6 min
What Is GHK-Cu? The Blue-Green Tripeptide Pulled From Human Blood
Skin & matrix
What Is GHK-Cu? The Blue-Green Tripeptide Pulled From Human Blood

A three-amino-acid copper complex, first isolated from human plasma in 1977, has become one of the most-studied small peptides in skin and matrix biology. Here is what the research actually shows — and where it goes quiet.

6 min
What Is Retatrutide? The Triple-Agonist Peptide Rewriting Metabolic Pharmacology
Metabolic & longevity
What Is Retatrutide? The Triple-Agonist Peptide Rewriting Metabolic Pharmacology

Retatrutide (LY3437943) is a single engineered peptide built to pull three metabolic levers at once. Here is what the science actually shows — and why a research-grade compound is not the same thing as an approved medicine.

6 min
The FDA’s July 2026 Peptide Review, Explained
Regulation
The FDA’s July 2026 Peptide Review, Explained

A US advisory committee meets on 23–24 July 2026 to weigh whether a group of research peptides — including BPC-157 and TB-500 — should return to a category permitting regulated compounding. Here is what is actually being decided, and what it does not change.

6 min