Lyophilised · ≥99% (HPLC) ·
Supplied lyophilised. Reconstitution typically uses bacteriostatic water.
SS-31 (Elamipretide) is a synthetic tetrapeptide aromatic-cationic compound with the sequence D-Arg-Dmt-Lys-Phe-NH₂ (Dmt = 2′,6′-dimethyltyrosine), designed to target and stabilise cardiolipin on the inner mitochondrial membrane; CAS 736992-21-5; molecular weight 639.8 g/mol; studied in models of mitochondrial dysfunction, oxidative stress attenuation, and neuroprotection. For laboratory research use only; not for human or veterinary use.
Mitochondria power nearly every cell, and when their inner membranes falter, so does the tissue around them. SS-31, known generically as elamipretide, is a synthetic, cell-permeable tetrapeptide designed to concentrate in the inner mitochondrial membrane. It has become one of the most closely studied mitochondria-targeted peptides in bioenergetics research, and recently reached a regulatory milestone as the first cardiolipin-directed mitochondrial therapeutic to gain approval (Shirley et al., 2026).
A peptide that homes to the mitochondrion. Elamipretide's alternating aromatic-cationic structure allows it to cross cell membranes and associate selectively with cardiolipin, a signature phospholipid of the inner mitochondrial membrane. By binding cardiolipin, it is proposed to stabilize cristae architecture and support electron transport chain organization, thereby improving bioenergetic efficiency and reducing reactive oxygen species generation (Sabbah et al., 2025; Tung et al., 2025). This mechanism makes SS-31 a precise tool for interrogating mitochondrial contributions to cellular stress.
What the research explores. Investigations span multiple model systems:
These findings arise from in vitro, animal, and clinical research and describe biological activity rather than human safety or efficacy outcomes outside the approved indication. Full citations are listed under the Scientific References tab.
Physicochemical profile. CAS 736992-21-5 · Molecular formula C₃₂H₄₉N₉O₅ · Molecular weight 639.8 g/mol · Sequence D-Arg-Dmt-Lys-Phe-NH₂ · Appearance: white lyophilized powder · Soluble in water.
Specification & quality. Each individually sealed vial contains 10 mg of SS-31 (elamipretide) as a white lyophilized powder at ≥99% purity by HPLC. Every batch is third-party tested, with a Certificate of Analysis (COA) available. Store at −20 °C, protected from light and moisture.
This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.
Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.
Certificate of Analysis — lot-specific COA ships with every order and is available on request.
Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.
References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.
SS-31, also called Elamipretide, is a synthetic mitochondria-targeting tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) that selectively associates with cardiolipin on the inner mitochondrial membrane. It is a widely studied tool in mitochondrial bioenergetics research. Condor Research supplies it as a 10 mg lyophilized vial at ≥99% HPLC purity, strictly for in-vitro laboratory research use only.
SS-31 is a four-residue peptide that binds cardiolipin and acts directly at the inner mitochondrial membrane, while MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial genome that signals more broadly in metabolic regulation. Both are mitochondrial research tools but act at different levels. Each is a separate ≥99% HPLC, research-use-only reference compound.
SS-31 (Elamipretide) is a cardiolipin-binding peptide that localizes to the inner mitochondrial membrane, whereas NAD+ is a fundamental redox coenzyme central to cellular energy metabolism. One is a membrane-targeting reference peptide, the other a metabolic cofactor; they are studied for complementary but distinct aspects of bioenergetics. Both are supplied strictly as research-use-only reference materials.
SS-31 is a mitochondria-targeting tetrapeptide that associates with cardiolipin, while AICAR is a small-molecule activator of AMP-activated protein kinase (AMPK), the cell's energy sensor. One targets the mitochondrial membrane directly; the other acts on an upstream signalling enzyme. Researchers select between them by mechanism. Both are offered as ≥99% HPLC, research-use-only reference compounds.
SS-31 is selected when the research target is specifically cardiolipin and the inner mitochondrial membrane, a mechanism distinct from genome-encoded peptides like MOTS-c or metabolic activators like AICAR. Its small, defined tetrapeptide structure makes it a focused reference tool. As with all catalog items, it is for in-vitro research only, with no human or veterinary use.
SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide that acts at cardiolipin, whereas Pinealon is a short Glu-Asp-Arg tripeptide bioregulator studied in neuroprotection and longevity contexts. They appear together under neuroprotective research themes but address different molecular targets. Condor Research offers both as separate ≥99% HPLC, research-use-only reference materials for laboratory study.
Yes. The non-standard residues — D-arginine and 2,6-dimethyltyrosine (Dmt) — and the full amidated sequence (D-Arg-Dmt-Lys-Phe-NH2, CAS 736992-21-5) are verified for each lot by an independent third-party laboratory using HPLC for purity and mass spectrometry for identity. Results are documented on the batch-specific Certificate of Analysis available on request.
Yes. SS-31 is supplied strictly for laboratory research use only (in vitro). It is not a medicine, food, supplement, cosmetic, or medical device, and is not for human or veterinary use, administration, or consumption. Condor Research provides no dosing, protocols, or human-use guidance. Purchase is limited to qualified professionals and institutions aged 18 or over.
Yes. Each SS-31 lot is tested by an independent third-party laboratory by HPLC for identity and purity, with mass spectrometry confirmation, and ships against a batch-specific Certificate of Analysis verifying ≥99% purity. To request the COA for the current lot before ordering, contact info@condorresearch.com.
For analytical laboratory preparation only, SS-31 is water-soluble and can be reconstituted with a sterile aqueous diluent; the chosen volume sets the working concentration. Store the sealed lyophilized vial at -20°C, protected from light, with a 24-month shelf life from manufacture. This is laboratory handling information, not guidance for any human or animal use.
No marketing fluff — just characterised material with paperwork. The data sheet and CAS matched our records precisely.
Lyophilised cake was uniform and dissolved fully. Would appreciate a digital COA portal, but the PDF on request worked fine.
Identity by MS confirmed in our facility. Communication around storage and handling was precise and professional.
Reconstitution was clean with no visible particulates. The lot-specific COA matched the assay we ran in-house — purity is exactly as stated.
We verify every incoming compound by HPLC; this batch came back within tolerance of the certificate. Dispatch from the EU warehouse was quick.
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