Research use only · EU-warehoused · COA on every batch · HPLC ≥99% · Shipment 2–5 days
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NAD+

NAD+

Lyophilised · ≥99% (HPLC) ·

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Supplied lyophilised. Reconstitution typically uses bacteriostatic water.

How to reconstitute NAD+ — stock calculator
Independently third-party tested · COA on every batch · 48h EU dispatch
[01]

Overview

NAD+ (nicotinamide adenine dinucleotide) is a fundamental redox coenzyme at the centre of cellular-energy metabolism and longevity research, serving as an essential substrate for sirtuin and PARP enzymes. It is a dinucleotide, not a peptide. CAS 53-84-9; molecular formula C21H27N7O14P2; molecular weight approximately 663.4 g/mol; supplied lyophilised at ≥99% by HPLC. For laboratory research use only.

Present in every living cell, NAD+ (nicotinamide adenine dinucleotide) is a fundamental coenzyme that sits at the centre of cellular energy metabolism. It is not a peptide but a dinucleotide — built from nicotinamide and adenine ribonucleotides — and it has become one of the most actively studied molecules in metabolism, mitochondrial-function, and ageing research, where its decline with age is a recurring focus.

A coenzyme at the centre of metabolism. NAD+ functions both as an electron carrier in redox reactions and as a substrate consumed by signalling enzymes such as sirtuins and CD38. Contemporary work frames it as a central metabolic hub whose availability is tied to many of the molecular hallmarks of ageing (Pei et al., 2026), which has driven broad interest in NAD+ metabolism across disease biology (Zhang et al., 2026).

What the research explores. Across cell-culture and animal systems, NAD+ biology is investigated along several interlocking themes:

  • Mitochondrial & cytoprotective signalling — studied for how mitochondrial NAD+ transport influences ischemia/reperfusion injury and bioenergetics (Wang et al., 2026).
  • Cardiovascular & metabolic regulation — examined for its role in cardiovascular disease and the NAD+-SIRT3 metabolic-memory axis (Prasanna et al., 2026; Zhang et al., 2026).
  • Cellular ageing & sirtuin-linked dynamics — explored as a modulator of microtubule and mitochondrial function via sirtuin signalling (Cui et al., 2026).

The activity described here is drawn from in-vitro and animal studies; it characterises biological behaviour in experimental models and does not establish efficacy or safety in humans. Full citations are listed under the Scientific References tab.

Physicochemical profile. CAS No. 53-84-9 · Molecular formula C21H27N7O14P2 · Molecular weight 663.43 g/mol · Appearance: white lyophilized powder · Solubility: soluble in water at 10 mg/mL.

Specification & quality. Each individually sealed vial contains 1000 mg of NAD+ as a white lyophilized powder at ≥99% purity by HPLC. Every batch is third-party tested, and a Certificate of Analysis (COA) is available. Store at −20 °C, protected from light and moisture; shelf life 24 months from the manufacture date.

This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.

Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.

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Quality & COA

Certificate of Analysis
Lot-specific COA with every order

Certificate of Analysis — lot-specific COA ships with every order and is available on request.

Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.

HPLC purity
≥99% (HPLC)
Method
HPLC + MS
Endotoxin
Reported
[02]

Data Sheet

CAS number53-84-9
Molecular formulaC21H27N7O14P2
Molecular weight663.43
Purity≥99% (HPLC)
Physical formWhite lyophilized powder
Quantity500mg/vial
SolubilitySoluble in water at 10mg/mL
StorageStore at -20°C, protect from light
ReconstitutionReconstitute with sterile water.
Shelf life24 months from manufacture date
OriginEU · Slovakia
ClassificationResearch use only
[03]

Scientific References

01 Zhang Y, Wang Y, Qiao Y, Liu L, Zhao H, Jin Q et al. Targeting the NAD(+)-SIRT3 axis to mitigate metabolic memory in diabetic kidney disease. Renal failure. 2026;48(1):2648912. PMID: 41991506. doi:10.1080/0886022X.2026.2648912. PubMed 02 Prasanna J, Manickam R, Tipparaju SM Role of nicotinamide adenine dinucleotide in cardiovascular disease. Current opinion in cardiology. 2026;41(4):369-376. PMID: 42047243. doi:10.1097/HCO.0000000000001292. PubMed 03 Zhang Z, Ansari AJ, Fayne ER, Zhang Y Emerging chemical strategies for CD38 inhibition: restoring NAD(+) metabolism and disease control. Bioorganic & medicinal chemistry. 2026;138:118676. PMID: 42033923. doi:10.1016/j.bmc.2026.118676. PubMed 04 Pei Z, Liang F, Wang X, Li H NAD⁺ as a central metabolic hub Regulating the hallmarks of aging: Mechanisms and therapeutic implications. Mechanisms of ageing and development. 2026;231:112174. PMID: 41812700. doi:10.1016/j.mad.2026.112174. PubMed 05 Luo J, Wang S, Lin X, Wang T, Li J, Jiang D et al. Nicotinamide mononucleotide (NMN) improves the ovarian microenvironment associated with oocyte quality by increasing estrogen signaling, reprogramming ovarian metabolism, reducing oxidative stress, and inhibiting apoptosis in the spotted scat (Scatophagus argus). Theriogenology. 2026;262:117980. PMID: 42105622. doi:10.1016/j.theriogenology.2026.117980. PubMed 06 Wu Y, Yu J Overexpression of NMNAT3 suppresses melanoma progression by reprogramming NAD⁺ metabolism. Translational oncology. 2026;69:102562. PMID: 42068671. doi:10.1016/j.tranon.2025.102562. PubMed 07 Li K, Sun D, Zhang D, Liu Y, Li X High-titer nicotinamide adenine dinucleotide production via artificially designed pseudo-de novo biosynthesis pathway. Bioresource technology. 2026;451:134529. PMID: 41916456. doi:10.1016/j.biortech.2026.134529. PubMed 08 Ciampa EJ, Machado LM, Lee KJ, Clark AJ, Vu KQ, Khan NA et al. Placental nicotinamide adenine dinucleotide modulates the timing of labor. Science (New York, N.Y.). 2026;392(6803):1194-1199. PMID: 42275500. doi:10.1126/science.adz1624. PubMed 09 Boyle E, Zhang O, Cen Y Enzymatic Synthesis of NAD(). Current protocols. 2026;6(6):e70397. PMID: 42258046. doi:10.1002/cpz1.70397. PubMed 10 Cao F, Ge X, Pi A, Huang Q, Pei L, Chen R et al. Hepatic Hamp restoration contributes to nicotinamide mononucleotide (NMN)-alleviated hepatic steatosis in chronic alcohol-fed mice. Communications biology. 2026. PMID: 42225972. doi:10.1038/s42003-026-10398-3. PubMed 11 Kang S, Wei S, Koo BI, Jo Y, Park J, Xue Y et al. Ion-coupled transfersome complexes for enhanced transdermal NAD(+) repletion and mitigation of cellular senescence signatures. Materials today. Bio. 2026;38:103218. PMID: 42170234. doi:10.1016/j.mtbio.2026.103218. PubMed 12 Kim JH, Park SJ, Lee JA, Cheon CK PRPS1 (p.V42L) Mutation in Arts Syndrome Induces Aberrant Neural Stem Cell Development and Neuronal Senescence-Like Phenotype: Rescue by Nicotinamide Mononucleotide Supplementation. International journal of stem cells. 2026;19(2):186-196. PMID: 41787648. doi:10.15283/ijsc25127. PubMed 13 Wang X, Li Y, Tan J, Sun X, Zhou Q, Xu R et al. Mitochondrial NAD(+) Transport Alleviates Cerebral Ischemia/Reperfusion Injury via Enhancement of Mitochondrial Function. Antioxidants & redox signaling. 2026;:15230864261455714. PMID: 42209413. doi:10.1177/15230864261455714. PubMed 14 Venkateshvaran A, Pundlik SS, Suresh Y, Hegde A, Venkatesh B, Dowari S et al. Dose-Dependent Effects of Dihydronicotinamide Riboside on Human Engineered Skeletal Muscle Development. ACS biomaterials science & engineering. 2026. PMID: 42206993. doi:10.1021/acsbiomaterials.5c02051. PubMed 15 Cui J, Ren S, Wang B, Zhang N, Zhu S, Zhang Y et al. NMN/NAD(+) enhances SIRT2-modulated microtubule dynamics to improve mitochondrial and mitophagy functions in senescent cells. Autophagy. 2026;:1-19. PMID: 42178923. doi:10.1080/15548627.2026.2677181. PubMed

References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.

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FAQ

NAD+ (nicotinamide adenine dinucleotide) is a fundamental coenzyme present in every living cell, central to cellular energy metabolism and redox reactions. It is supplied at 1000 mg/vial as a single defined molecule (CAS 53-84-9). Condor offers it strictly as a Research Use Only reference compound for in vitro and animal studies.

NAD+ is a single defined molecule, nicotinamide adenine dinucleotide (formula C21H27N7O14P2, MW 663.43, CAS 53-84-9), not a multi-component mixture. Its catalog type label differs from peptide vials, but it is one compound tested to >=99% by HPLC with a batch Certificate of Analysis. Supplied for research use only.

NAD+ is the coenzyme itself, central to cellular energy and redox metabolism. 5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that sits at a crossroads of methylation and NAD+ metabolism. One is the cofactor, the other a tool that modulates a related enzyme. Research use only.

NAD+ is a small-molecule coenzyme central to energy metabolism and redox reactions. MOTS-c is a 16-amino-acid mitochondrial-derived peptide studied as a metabolic signaling molecule. They differ in chemical class, cofactor versus peptide signal, so they probe distinct aspects of metabolism and longevity research. Both are supplied strictly for research use only.

NAD+ is a coenzyme central to cellular redox and energy metabolism. AICAR is a small-molecule activator of AMP-activated protein kinase (AMPK), the cell's energy sensor. One supplies a fundamental cofactor to the system; the other activates a key regulatory enzyme. They are complementary tools in metabolic research, supplied for research use only.

Yes. Condor Research supplies NAD+ strictly as a Research Use Only (in vitro) reference compound to professionals and institutions, not as a supplement, anti-aging product or anything for human or veterinary use. Buyers are responsible for confirming import legality in their own country. Questions: info@condorresearch.com.

NAD+ is listed as soluble in water at 10 mg/mL. To dissolve the full 1000 mg at that reference concentration, add 100 mL of diluent in the lab; use a smaller proportional volume for partial amounts or higher concentrations. This is for in vitro research preparation only, not human or veterinary use.

Store the sealed NAD+ vial at -20C, protected from light; shelf life is 24 months from manufacture. NAD+ is sensitive to hydrolysis and oxidation, so prepared solutions should be handled cold, protected from light and used promptly. For batch stability details, contact info@condorresearch.com. Research preparation only, not human use.

The product ships lyophilized in a sealed vial and is stored at -20C, protected from light, which limits the hydrolysis and oxidation NAD+ is prone to; shelf life is 24 months. Each batch is HPLC-tested to >=99% with a Certificate of Analysis. For specific stability data, contact info@condorresearch.com.

Yes. Each NAD+ batch is tested by an independent third-party laboratory by HPLC for identity and purity (>=99%) and ships with a lot-specific Certificate of Analysis confirming the material matches the stated specification. To request the COA for a given lot before ordering, contact info@condorresearch.com.

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Reviews

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4.7
76 verified reviews
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Apr 2026
High purity, clear labelling

Lyophilised cake was uniform and dissolved fully. Would appreciate a digital COA portal, but the PDF on request worked fine.

Dr. A. Bianchi · University · IT Verified purchase
Mar 2026
Trustworthy supplier

Identity by MS confirmed in our facility. Communication around storage and handling was precise and professional.

K. Wójcik · Research group · PL Verified purchase
Mar 2026
Reference-grade consistency

Reconstitution was clean with no visible particulates. The lot-specific COA matched the assay we ran in-house — purity is exactly as stated.

Dr. M. Hartmann · Research lab · DE Verified purchase
Feb 2026
COA matched our own HPLC

We verify every incoming compound by HPLC; this batch came back within tolerance of the certificate. Dispatch from the EU warehouse was quick.

L. Fischer · University group · AT Verified purchase

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