Lyophilised · ≥99% (HPLC) ·
Supplied lyophilised. Reconstitution typically uses bacteriostatic water.
Epitalon (Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) analogue of the endogenous pineal polypeptide complex epithalamin, studied for its role in telomerase activation, telomere elongation, and neuroendocrine regulation in in vitro and animal models. CAS 307297-39-8; molecular formula C14H22N4O9; molecular weight 390.35 g/mol. For laboratory research use only; not for human or veterinary use.
In the centre of the brain sits the pineal gland, a structure that shrinks and slows with age. From an extract of that gland — epithalamin — Soviet researchers distilled a sequence of just four amino acids and synthesised it anew. That sequence is Epitalon (AEDG), a tetrapeptide that has since become one of the most-studied tools in the laboratory science of cellular ageing.
A synthetic peptide modelled on the pineal gland. Epitalon's appeal to researchers lies in its smallness: four residues, Ala-Glu-Asp-Gly, short enough to be a clean experimental probe yet biologically active in cell and animal systems. A dedicated review has catalogued it as a highly bioactive pineal tetrapeptide of broad research interest (Araj et al., 2025), and its place within the wider field of peptide bioregulators studied for healthy-ageing endpoints has been mapped in the gerontology literature (Mavrych et al., 2026).
What the research explores. Across cell-culture and animal systems, Epitalon has been investigated along several converging lines:
The activity described here is drawn from in-vitro and animal studies; it characterises biological behaviour in experimental models and does not establish efficacy or safety in humans. Full citations are listed under the Scientific References tab.
Physicochemical profile. CAS No. 307297-39-8 · Molecular formula C14H22N4O9 · Molecular weight 390.35 g/mol · Sequence Ala-Glu-Asp-Gly (4 aa) · Appearance: White lyophilized powder · Solubility: Soluble in water.
Specification & quality. Each bottle contains 60 HPMC (vegan) capsules, each providing 10mg of Epitalon at ≥99% (HPLC). Encapsulated — no reconstitution required. Every batch is independently third-party tested, and a Certificate of Analysis (COA) is available. Store at -20°C, protect from light and moisture; shelf life 24 months from the manufacture date. EU warehoused.
This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.
Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.
Certificate of Analysis — lot-specific COA ships with every order and is available on request.
Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.
References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.
Epitalon (AEDG) is a synthetic tetrapeptide modelled on the natural pineal extract epithalamin, investigated for telomerase activity, gene-expression and ageing-related endpoints in cell and animal models. Its short four-residue sequence makes it a widely used experimental probe in laboratory ageing research. Condor Research supplies it strictly as a Research Use Only reference compound for in vitro and animal studies, not as a medicine, supplement or product for human or veterinary use.
Epitalon is a four-residue tetrapeptide (Ala-Glu-Asp-Gly) studied mainly for telomerase and cellular-ageing endpoints, while Pinealon is a three-residue tripeptide (Glu-Asp-Arg) studied chiefly for neuroprotection and antioxidant defence in neuronal models. They are related members of the short-peptide bioregulator field but have distinct sequences and research focuses. Both are supplied only as research-use-only reference compounds.
Epitalon is studied for systemic ageing markers such as telomere length and pineal/circadian regulation, whereas Cortagen (AEDP) is a cytogen-class peptide associated in research with peripheral nerve and connective tissue. Each bioregulator is investigated for tissue- or pathway-specific questions rather than a single shared effect. All are offered exclusively for laboratory research use, not for human or veterinary use.
No — they belong to entirely different chemical classes. Epitalon is a four-amino-acid peptide studied for telomerase and gene-expression endpoints, while NMN is a nucleotide precursor studied in NAD+ metabolism pathways. They probe different mechanistic questions in ageing-related research and are not interchangeable. Both are supplied solely as Research Use Only reference compounds.
Yes. Condor Research supplies Epitalon strictly as a Research Use Only reference compound to professionals and institutions, not as a medicine, supplement or product for human or veterinary use. Buyers are responsible for confirming import legality in their own country. Questions: info@condorresearch.com.
The capsule is a pre-weighed, encapsulated solid format that makes a fixed quantity of reference compound convenient to store, inventory and handle in the laboratory. Each HPMC (vegan) capsule holds an accurately measured amount of material with no reconstitution required. This format is purely a research handling convenience and does not imply or permit any form of consumption. For laboratory research use only. Not for human or veterinary use.
No. The compound is already encapsulated as a solid lyophilized powder, so no reconstitution is needed for storage or handling. Researchers preparing experimental solutions follow their own validated protocols; Epitalon is described as water-soluble. It is a laboratory reference material for research use only and not for human or veterinary use.
Each bottle contains 60 HPMC (vegan) capsules, with 10mg of Epitalon per capsule at ≥99% HPLC purity. Every batch is independently third-party tested. The per-capsule quantity is the mass of reference compound for laboratory measurement only and is not a dose for human or veterinary use.
Epitalon has CAS No. 307297-39-8, molecular formula C14H22N4O9 and a molecular weight of 390.35 g/mol, with the sequence Ala-Glu-Asp-Gly (4 aa). It presents as a white lyophilized powder that is soluble in water. These specifications are provided for research characterisation purposes only.
Yes. Every Epitalon batch is tested by an independent third-party laboratory by HPLC for identity and purity (≥99%), and each lot ships with a lot-specific Certificate of Analysis. To request the COA for your batch, contact info@condorresearch.com. The COA documents analytical quality for research use only.
Store at -20°C, protected from light and moisture, to preserve compound integrity across the stated 24-month shelf life from the manufacture date. The product is EU warehoused to support stability in transit. It is supplied for laboratory research use only and is not for human or veterinary use, ingestion, or diagnostic application.
No marketing fluff — just characterised material with paperwork. The data sheet and CAS matched our records precisely.
Lyophilised cake was uniform and dissolved fully. Would appreciate a digital COA portal, but the PDF on request worked fine.
Identity by MS confirmed in our facility. Communication around storage and handling was precise and professional.
Reconstitution was clean with no visible particulates. The lot-specific COA matched the assay we ran in-house — purity is exactly as stated.
We verify every incoming compound by HPLC; this batch came back within tolerance of the certificate. Dispatch from the EU warehouse was quick.
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