Research use only · EU-warehoused · COA on every batch · HPLC ≥99% · Shipment 2–5 days
Log in Register
Home/ Catalogue/ Encapsulated Compounds/ Vesugen Capsules
In stock
Vesugen Capsules

Vesugen Capsules

Lyophilised · ≥99% (HPLC) ·

Quantity Volume discounts auto-applied
Custom quantity
1

Supplied lyophilised. Reconstitution typically uses bacteriostatic water.

Independently third-party tested · COA on every batch · 48h EU dispatch
[01]

Overview

Vesugen is a synthetic tripeptide bioregulator (Lys-Glu-Asp; sequence L-Lysyl-L-glutamyl-L-aspartic acid) derived from the vascular wall, developed within the Khavinson peptide bioregulator programme and studied in models of vascular endothelium function, angiogenesis, and cardiovascular tissue regulation. Molecular formula C15H26N4O8; molecular weight 390.39 g/mol; purity HPLC ≥99%. Supplied as encapsulated powder for laboratory research use only; not for human or veterinary use.

The shortest peptides in the cytogen family encode their proposed selectivity in just three letters. Vesugen is the tripeptide Lys-Glu-Asp (KED), a short peptide bioregulator that research has associated specifically with the vascular wall. Like its cytogen relatives, it sits in a small, early-stage literature, and we present it plainly as an experimental reference compound rather than a proven one.

A vascular-associated cytogen peptide. The interest in KED rests on the broader hypothesis that very short peptides can act as tissue-selective regulators of gene expression. The sequence has been examined for molecular-genetic effects on neurogenesis-related signalling in disease models (Khavinson et al., 2021), and KED appears within wider studies of how short peptides modulate gene expression in ageing human mesenchymal stem-cell cultures (Ashapkin et al., 2020). These remain mechanistic, model-system observations.

What the research explores. Across cell-culture and animal systems, Vesugen has been investigated along several converging lines:

  • Gene-expression & epigenetic regulation — studied for modulation of gene expression in ageing stem-cell cultures and for epigenetic effects on aged chromatin (Ashapkin et al., 2020; Lezhava et al., 2020).
  • Neuro- and tissue-maintenance models — examined for molecular-genetic aspects of neurogenesis regulation and protection of fibroblast-derived induced neurons (Khavinson et al., 2021; Kraskovskaya et al., 2024).
  • Cellular-ageing assays — explored alongside related short peptides for protection of ageing oral stem cells (Sinjari et al., 2020).

The activity described here is drawn from in-vitro and animal studies; it characterises biological behaviour in experimental models and does not establish efficacy or safety in humans. Full citations are listed under the Scientific References tab.

Physicochemical profile. Molecular formula C15H26N4O8 · Molecular weight 390.39 g/mol · Sequence Lys-Glu-Asp (3 aa) · Appearance: White lyophilized powder · Solubility: Soluble in water.

Specification & quality. Each bottle contains 60 HPMC (vegan) capsules, each providing 10mg of Vesugen at ≥99% (HPLC). Encapsulated — no reconstitution required. Every batch is independently third-party tested, and a Certificate of Analysis (COA) is available. Store at -20°C, protect from light and moisture; shelf life 24 months from the manufacture date. EU warehoused.

This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.

Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.

[04]

Quality & COA

Certificate of Analysis
Lot-specific COA with every order

Certificate of Analysis — lot-specific COA ships with every order and is available on request.

Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.

HPLC purity
≥99% (HPLC)
Method
HPLC + MS
Endotoxin
Reported
[02]

Data Sheet

Molecular formulaC15H26N4O8
Molecular weight390.39
SequenceLys-Glu-Asp (3 aa)
Purity≥99% (HPLC)
Physical formWhite lyophilized powder
Quantity60 capsules
SolubilitySoluble in water
StorageStore at -20°C, protect from light and moisture
ReconstitutionEncapsulated — no reconstitution required.
Shelf life24 months from manufacture date
Dose per capsule10mg
Capsule materialHPMC (Vegan)
OriginEU · Slovakia
ClassificationResearch use only
[03]

Scientific References

01 Ilina AR, Popovich IG, Ryzhak GA, Khavinson VK [Prospects for use of short peptides in pharmacotherapeutic correction of Alzheimer's disease.]. Advances in gerontology = Uspekhi gerontologii. 2024;37(1-2):10-20. PMID: 38944767. PubMed 02 Khavinson VK, Lin'kova NS, Umnov RS Peptide KED: Molecular-Genetic Aspects of Neurogenesis Regulation in Alzheimer's Disease. Bulletin of experimental biology and medicine. 2021;171(2):190-193. PMID: 34173097. doi:10.1007/s10517-021-05192-6. PubMed 03 Kuznik BI, Khavinson VK, Tarnovskaya SI, Linkova NS, Kozina LS, Dyakonov MM [Adhesion molecule JAM-A, its function and mechanism of epigenetic regulation]. Advances in gerontology = Uspekhi gerontologii. 2015;28(4):656-668. PMID: 28509452. PubMed 04 Khavinson VKh, Kuznik BI, Linkova NS, Kolchina NV [The Role of Cytokines MIC-1/GDF15 in Development of the Old Age Disease]. Uspekhi fiziologicheskikh nauk. 2015;46(4):38-52. PMID: 27183783. PubMed 05 Liu Y, Nadig I, Mehta AS, Chuo SW, Ho YH, Tyler J et al. Precision Labeling of Native Antibodies with Lock Coupling. Journal of the American Chemical Society. 2026;148(1):2008-2015. PMID: 41432463. doi:10.1021/jacs.5c20725. PubMed 06 Patil G, Frasko P, Lier B, Gabler T, Furtmüller PG, Oostenbrink C et al. One single hydrogen bond guarantees conformational stability and activity in coproheme decarboxylase from Corynebacterium diphtheriae. Journal of inorganic biochemistry. 2025;273:113022. PMID: 40803046. doi:10.1016/j.jinorgbio.2025.113022. PubMed 07 Dobriţescu A, Samide A, Cioateră N, Mic OC, Ionescu C, Dăbuleanu I et al. The Inhibitory Effect and Adsorption Properties of Testagen Peptide on Copper Surfaces in Saline Environments: An Experimental and Computational Study. Molecules (Basel, Switzerland). 2025;30(15). PMID: 40807317. doi:10.3390/molecules30153141. PubMed 08 Kraskovskaya N, Linkova N, Sakhenberg E, Krieger D, Polyakova V, Medvedev D et al. Short Peptides Protect Fibroblast-Derived Induced Neurons from Age-Related Changes. International journal of molecular sciences. 2024;25(21). PMID: 39518916. doi:10.3390/ijms252111363. PubMed 09 Lezhava T, Jokhadze T, Monaselidze J, Buadze T, Gaiozishvili M, Sigua T et al. EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON THE "OLD" CHROMATIN. Georgian medical news. 2023;(335):79-83. PMID: 37042594. PubMed 10 Friedrich L, Kikuchi Y, Matsuda Y, Binder U, Skerra A Efficient secretory production of proline/alanine/serine (PAS) biopolymers in Corynebacterium glutamicum yielding a monodisperse biological alternative to polyethylene glycol (PEG). Microbial cell factories. 2022;21(1):227. PMID: 36307781. doi:10.1186/s12934-022-01948-5. PubMed 11 Kumar A, Alom SE, Ahari D, Priyadarshi A, Ansari MZ, Swaminathan R Role of Charged Amino Acids in Sullying the Fluorescence of Tryptophan or Conjugated Dansyl Probe in Monomeric Proteins. Biochemistry. 2022;61(5):339-353. PMID: 35107253. doi:10.1021/acs.biochem.1c00753. PubMed 12 Khavinson V, Ilina A, Kraskovskaya N, Linkova N, Kolchina N, Mironova E et al. Neuroprotective Effects of Tripeptides-Epigenetic Regulators in Mouse Model of Alzheimer's Disease. Pharmaceuticals (Basel, Switzerland). 2021;14(6). PMID: 34071923. doi:10.3390/ph14060515. PubMed 13 Sinjari B, Diomede F, Khavinson V, Mironova E, Linkova N, Trofimova S et al. Short Peptides Protect Oral Stem Cells from Ageing. Stem cell reviews and reports. 2020;16(1):159-166. PMID: 31677028. doi:10.1007/s12015-019-09921-3. PubMed 14 Ashapkin V, Khavinson V, Shilovsky G, Linkova N, Vanuyshin B Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides. Molecular biology reports. 2020;47(6):4323-4329. PMID: 32399807. doi:10.1007/s11033-020-05506-3. PubMed 15 Lezhava T, Jokhadze T, Monaselidze J, Buadze T, Gaiozishvili M, Sigua T EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON "AGED" HETEROCHROMATIN. Georgian medical news. 2020;(309):120-124. PMID: 33526740. PubMed

References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.

[05]

FAQ

Vesugen (KED) is a short three-amino-acid peptide of the cytogen bioregulator class, associated in research with the vascular wall and studied for endothelial gene-expression and tissue-maintenance endpoints in experimental models. Its published literature is small and preclinical in character. Condor Research supplies it strictly as a Research Use Only reference compound for in vitro and animal studies, not as a medicine, supplement or product for human or veterinary use.

Both are three-residue cytogen-class peptides studied in early-stage models, but their proposed tissue associations differ: Vesugen (KED, Lys-Glu-Asp) is linked in research to the vascular wall, while Pinealon (EDR, Glu-Asp-Arg) is examined in neuronal and brain-ageing models. They probe different research questions despite a shared peptide class. Both are supplied only as research-use-only reference compounds.

Vesugen (KED) is a tripeptide associated in research with vascular tissue, whereas Cortagen (AEDP) is a tetrapeptide associated with peripheral nerve and connective tissue. Each is investigated for tissue- and pathway-specific gene-expression endpoints rather than a single shared effect, and both rest on narrow preclinical literatures. Each is offered exclusively for laboratory research use, not for human or veterinary use.

No. Vesugen is a three-residue vascular-associated cytogen peptide, while Epitalon is a four-residue pineal-derived tetrapeptide studied for telomerase and ageing endpoints. They differ in sequence, proposed tissue selectivity and research focus, and address distinct experimental questions. Both are supplied solely as Research Use Only reference compounds.

Yes. Condor Research supplies Vesugen strictly as a Research Use Only reference compound to professionals and institutions, not as a medicine, supplement or product for human or veterinary use. Buyers are responsible for confirming import legality in their own country. Questions: info@condorresearch.com.

Vesugen is an experimental peptide with a narrow, predominantly preclinical literature focused on cell-culture and gene-expression model systems (Khavinson et al., 2021; Ashapkin et al., 2020). Its proposed vascular selectivity is a research hypothesis, not an established effect in humans. We describe it honestly as a research probe, supplied for laboratory research use only and not for human or veterinary use.

The capsule is a pre-weighed, encapsulated solid format that makes a fixed quantity of reference compound convenient to store, inventory and handle in the laboratory. Each HPMC (vegan) capsule holds an accurately measured amount of material with no reconstitution required. The format is a research handling convenience and does not imply or permit any form of consumption. For laboratory research use only. Not for human or veterinary use.

Each bottle contains 60 HPMC (vegan) capsules, with 10mg of Vesugen per capsule at ≥99% HPLC purity. Every batch is independently third-party tested. The per-capsule quantity is the mass of reference compound for laboratory measurement only and is not a dose for human or veterinary use.

Vesugen has the molecular formula C15H26N4O8 and a molecular weight of 390.39 g/mol, with the sequence Lys-Glu-Asp (3 aa). A verified CAS number is not assigned for this compound, so none is listed. It presents as a white lyophilized powder that is soluble in water, and these specifications are provided for research characterisation purposes only.

Yes. Every Vesugen batch is tested by an independent third-party laboratory by HPLC for identity and purity (≥99%), and each lot ships with a lot-specific Certificate of Analysis. To request the COA for your batch, contact info@condorresearch.com. The COA documents analytical quality for research use only.

Store at -20°C, protected from light and moisture, to preserve compound integrity across the stated 24-month shelf life from the manufacture date. The product is EU warehoused to support stability in transit. It is supplied for laboratory research use only and is not for human or veterinary use, ingestion, or diagnostic application.

[06]

Reviews

Leave a review
Earn 250 points for a verified review (account required).
4.6
26 verified reviews
5
77%
4
15%
3
4%
2
0%
1
4%
Apr 2026
Reproducible across batches

Third order with Condor. Batch-to-batch variation is minimal, which matters for our longitudinal work. The mono-labelled vials are easy to track.

Dr. R. Costa · Academic lab · PT Verified purchase
Mar 2026
Exactly what research needs

No marketing fluff — just characterised material with paperwork. The data sheet and CAS matched our records precisely.

J. Meijer · Biotech R&D · NL Verified purchase
Mar 2026
High purity, clear labelling

Lyophilised cake was uniform and dissolved fully. Would appreciate a digital COA portal, but the PDF on request worked fine.

Dr. A. Bianchi · University · IT Verified purchase
Feb 2026
Trustworthy supplier

Identity by MS confirmed in our facility. Communication around storage and handling was precise and professional.

K. Wójcik · Research group · PL Verified purchase

Related compounds