Lyophilised · ≥99% (HPLC) ·
Supplied lyophilised. Reconstitution typically uses bacteriostatic water.
Growth hormone is released in pulses, and researchers have long sought signals that extend those pulses without erasing their rhythm. CJC-1295 DAC is a synthetic analog of growth hormone-releasing hormone (GHRH) built on the modified GRF(1-29) sequence and fitted with a Drug Affinity Complex (DAC) — a maleimidopropionyl group that binds covalently to circulating serum albumin. This albumin-binding feature is what sets the DAC version apart, dramatically extending its circulating half-life relative to non-DAC GHRH analogs and making it a key tool for studying sustained GH/IGF-1 axis stimulation.
An albumin anchor for a short-lived hormone. Native GHRH is cleared within minutes. By bioconjugating the GRF(1-29) peptide to albumin via the DAC linker, CJC-1295 DAC resists degradation and remains available far longer, the foundational principle demonstrated when hGRF(1-29)-albumin bioconjugates were shown to activate the GRF receptor (Jetté et al., 2005). This long-acting design lets researchers examine prolonged versus pulsatile GHRH signaling.
What the research explores. The literature characterizes the compound's endocrine pharmacology:
These findings derive from animal models, analytical chemistry, and early clinical research describing biological activity; they do not establish human safety or efficacy. Full citations are listed under the Scientific References tab.
Physicochemical profile. CAS 446262-90-4 · Molecular formula C₁₆₅H₂₆₉N₄₇O₄₆ · Molecular weight 3647.2 g/mol · Sequence: modified GRF(1-29) with a Lys-linked maleimidopropionyl Drug Affinity Complex (albumin-binding) · Appearance: white lyophilized powder · Soluble in water.
Specification & quality. Each individually sealed vial contains 10 mg of CJC-1295 DAC as a white lyophilized powder at ≥99% purity by HPLC. Every batch is third-party tested, with a Certificate of Analysis (COA) available. Store at −20 °C, protected from light and moisture.
This product is intended for laboratory research use only (RUO). It is not a drug, food, cosmetic, or dietary supplement, and is not for human or veterinary use, ingestion, or diagnostic application. Handling is restricted to qualified research professionals operating in an appropriately equipped laboratory.
Supplied for in-vitro laboratory research use only (RUO). Not a drug, food or supplement; not for human or veterinary use.
Certificate of Analysis — lot-specific COA ships with every order and is available on request.
Each lot is tested by an independent third-party laboratory for identity (mass spectrometry) and purity (HPLC). The Certificate of Analysis for your specific batch ships with the order and is available on request — no house data, no exceptions.
References are illustrative of the research literature surrounding this compound. All claims relate to in-vitro and animal models only.
CJC-1295 DAC is a synthetic long-acting analogue of growth-hormone-releasing factor: the Modified GRF (1-29) sequence joined to a Drug Affinity Complex (DAC), a maleimidopropionyl group that binds circulating albumin to greatly extend its duration in research models. Condor Research supplies it as a 10 mg lyophilized vial at ≥99% HPLC purity, for in-vitro laboratory use only.
The difference is the Drug Affinity Complex. CJC-1295 DAC carries an albumin-binding DAC moiety that markedly extends its half-life, while CJC-1295 no DAC (Modified GRF 1-29) lacks it and is much shorter-acting. The DAC version is also heavier (MW ~3647 vs ~3368). Condor Research offers each as a separate ≥99% HPLC, research-use-only reference compound.
Yes. The DAC version binds albumin to provide sustained, long-acting GHRH-analogue activity in research models, whereas the no-DAC version (Modified GRF 1-29) is short-acting and clears quickly. Researchers studying prolonged signalling pick the DAC form; those needing pulsatile, short-lived exposure choose no-DAC. Both are research-use-only reference compounds, supplied at ≥99% HPLC purity with batch COAs.
The added mass comes from the Drug Affinity Complex — the lysine-linked maleimidopropionyl group that lets CJC-1295 DAC bind albumin. This roughly 280-dalton addition accounts for the higher molecular weight versus CJC-1295 no DAC (Modified GRF 1-29). The acylated mass is confirmed by mass spectrometry on each lot. Both are research-use-only reference materials.
In research models, the albumin-binding DAC gives CJC-1295 DAC a long, sustained profile rather than the short, pulsatile exposure characteristic of CJC-1295 no DAC (Modified GRF 1-29). Researchers studying preserved pulsatility typically favor the no-DAC form. This describes in-vitro research pharmacology only; Condor Research provides no human-use guidance, dosing, or protocols.
CJC-1295 DAC is engineered for a long, sustained profile through albumin binding, whereas Sermorelin is the bare GRF(1-29) fragment with a very short half-life. Both are GHRH analogues, but the DAC moiety makes CJC-1295 DAC far longer-acting in research models. Condor Research supplies each as a separate ≥99% HPLC, research-use-only reference compound.
CJC-1295 DAC achieves its extended duration through an albumin-binding Drug Affinity Complex on a Modified GRF (1-29) backbone, while Tesamorelin is a GRF(1-44) analogue stabilized by an N-terminal hexenoyl cap. Both are studied for prolonged GHRH-analogue activity but via different stabilization strategies. Each is offered as a distinct ≥99% HPLC, research-use-only reference compound.
Yes. The Modified GRF (1-29) sequence with its lysine-linked albumin-binding DAC (CAS 446262-90-4) is verified for each lot by an independent third-party laboratory using HPLC for purity and mass spectrometry for identity and acylated mass. It ships against a batch-specific Certificate of Analysis verifying ≥99% purity, available on request at info@condorresearch.com.
Yes. CJC-1295 DAC is supplied strictly for laboratory research use only (in vitro). It is not a medicine, food, supplement, cosmetic, or medical device, and is not for human or veterinary use, administration, or consumption. Condor Research provides no dosing, protocols, or human-use guidance. Purchase is limited to qualified professionals and institutions aged 18 or over.
For analytical laboratory preparation only, CJC-1295 DAC is water-soluble and can be reconstituted with a sterile aqueous diluent; the chosen volume sets the working concentration. Store the sealed lyophilized vial at -20°C, protected from light, with a 24-month shelf life from manufacture. This is laboratory handling information, not guidance for any human or animal use.
We verify every incoming compound by HPLC; this batch came back within tolerance of the certificate. Dispatch from the EU warehouse was quick.
Cold-chain handling was respected end to end. Vials arrived sealed, labelled and intact. Documentation is the most thorough I've seen from an EU supplier.
Solubility and stability were as described. Knocked one star only because express shipping options are limited, but quality is not in question.
Third order with Condor. Batch-to-batch variation is minimal, which matters for our longitudinal work. The mono-labelled vials are easy to track.
No marketing fluff — just characterised material with paperwork. The data sheet and CAS matched our records precisely.
Cookies
We use strictly necessary cookies to run the store. With your consent we also use analytics (order attribution) and marketing (Omnisend) cookies. Read our Cookie Policy.
