Longevity Research Compounds

Longevity research compounds are reference materials studied in preclinical and early clinical models of cellular ageing — NAD⁺ metabolism, mitochondrial function, autophagy and telomere biology. This category groups the compounds most investigated across those pathways so researchers can compare mechanism, format and documentation in one place. Every item is supplied strictly as Research Use Only (RUO) material with a batch Certificate of Analysis; nothing here is intended for human or veterinary use.
Mechanisms investigated
Ageing research converges on a small set of molecular nodes, and these compounds map onto different ones — they are not interchangeable:

NAD⁺ precursors (NAD⁺, NMN): studied for restoring the age-declining NAD⁺ pool that supplies sirtuin and PARP activity.
Mitochondrial peptides (MOTS-c; SS-31 / elamipretide): investigated for bioenergetic signalling and mitochondrial stress response.
Autophagy inducers (spermidine): studied for proteostasis and cellular self-renewal.
Pineal / telomere-axis peptides (Epitalon, Pinealon): investigated for telomerase and circadian signalling.
Growth-axis compounds (IGF-1 LR3): studied at the muscle / mTOR interface.

Comparison
CompoundClassPathway / targetResearch focusFormat
NAD⁺CoenzymeNAD⁺ redox poolCellular-energy metabolismVial
NMNNAD⁺ precursorNAMPT / NAD⁺ salvageNAD⁺ restorationCapsules
MOTS-cMitochondrial-derived peptideAMPK / metabolic stressMitochondrial metabolismVial
SS-31 (Elamipretide)Mito-targeted peptideCardiolipin / inner membraneMitochondrial functionVial
SpermidinePolyamineAutophagy inductionProteostasis / autophagyVial
EpitalonPineal tetrapeptideTelomerase / pineal axisTelomere & circadian biologyVial / Caps
IGF-1 LR3GH-axis peptideIGF-1R / mTORMuscle & growth signallingVial

Comparison

Are longevity research compounds legal in Europe?

Legal status varies by compound and by member state. NAD⁺ is supplied strictly as research-use-only reference material; NMN's food status differs across the EU. See our per-compound legal guides for NAD⁺ and NMN.

What is the difference between NAD⁺, NMN and NR?

NAD⁺ is the coenzyme itself; NMN and NR are precursors the cell converts toward NAD⁺ through different salvage steps. Our NAD⁺/NMN/NR human-evidence article compares what each has actually been measured to do.

Do you provide a Certificate of Analysis for every batch?

Yes. Every compound ships as research-use-only material with a batch-specific COA covering identity and purity by HPLC and mass spectrometry.

NMN vs NAD⁺ — which is studied for what?

NAD⁺ is studied directly as the redox coenzyme; NMN is studied as an orally-relevant precursor intended to raise the NAD⁺ pool. See our NMN vs NAD⁺ comparison.

How are these compounds stored and reconstituted?

Storage and reconstitution differ by compound and format (vial vs capsule). See our storage and reconstitution guides for specifics.